SCHEMBL29280381

SCHEMBL29280381

O=C(O)CCC(NC/C=C/c1ccc(O)c(O)c1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
CYP3A4 P08684 2/20 0.44
RECQL P46063 1/20 0.44
HSD17B10 Q99714 3/20 0.43
MMP1 P03956 3/20 0.43
MMP2 P08253 3/20 0.43
MMP9 P14780 3/20 0.43
KDM4E B2RXH2 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
PTPN1 P18031 2/20 0.43
APP P05067 2/20 0.43
MEN1 O00255 1/20 0.43
HDAC3 O15379 1/20 0.43
CA12 O43570 1/20 0.43
AKR1B10 O60218 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
LMNA P02545 1/20 0.43
TTR P02766 1/20 0.43
GLA P06280 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30819187 1.00 ALDH1A1 (0.44) ALDH1A1CYP3A4RECQLHSD17B10MMP1
SCHEMBL2914248 0.84 GAA (0.50) ALDH1A1MMP9GAAFOLH1EPOR
SCHEMBL2914250 0.84 GAA (0.50) ALDH1A1MMP9GAAFOLH1EPOR
SCHEMBL3176982 0.80 CAPN1 (0.54) ALDH1A1CYP3A4HSD17B10MMP1MMP2
SCHEMBL30819205 0.80 CAPN1 (0.54) ALDH1A1CYP3A4HSD17B10MMP1MMP2
SCHEMBL3789459 0.80 CAPN1 (0.54) ALDH1A1CYP3A4HSD17B10MMP1MMP2
SCHEMBL10355087 0.71 FOLH1 (0.50) GAAFOLH1
SCHEMBL12231157 0.70 CAPN1 (0.52) ALDH1A1CYP3A4HSD17B10MMP1MMP2
(E)-3,4-Stilbendiol SCHEMBL27979125 0.70 PTPN1 (0.45) ALDH1A1CYP3A4RECQLHSD17B10MMP1
SCHEMBL15313369 0.70 FOLH1 (0.48) GAAFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117740961-A Compound analysis method of liquorice and liquorice probiotics fermentation preparation 北京中医药大学 2024-03-22 CN disclosed