Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | HTT | P42858 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | TYMS | P04818 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6126717 | 0.99 | HTT (0.74) | MEN1KMT2AALDH1A1HTTKDM4E | |
| SCHEMBL27854528 | 0.96 | MEN1 (0.74) | MEN1KMT2AALDH1A1HTTKDM4E | |
| SCHEMBL7435419 | 0.86 | KDM4E (0.72) | MEN1KMT2AALDH1A1HTTKDM4E | |
| SCHEMBL7437388 | 0.85 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1HTTKDM4E | |
| SCHEMBL9273857 | 0.85 | MEN1 (0.76) | MEN1KMT2AALDH1A1HTTKDM4E | |
| SCHEMBL8361521 | 0.84 | ALDH1A1 (1.00) | MEN1KMT2AALDH1A1HTTKDM4E | |
| SCHEMBL8357959 | 0.84 | ALDH1A1 (1.00) | MEN1KMT2AALDH1A1HTTKDM4E | |
| SCHEMBL9591254 | 0.83 | KDM4E (0.76) | MEN1KMT2AALDH1A1HTTKDM4E | |
| SCHEMBL6128980 | 0.83 | MEN1 (0.84) | MEN1KMT2AALDH1A1HTTKDM4E | |
| SCHEMBL27854540 | 0.82 | L3MBTL1 (0.69) | MEN1KMT2AALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117750959-A | 1, 2-dihydroquinolin-2-one for use in the treatment of limb muscular dystrophy | 高级科学研究委员会 | 2024-03-22 | — | — | CN | disclosed |