Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 7/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | GRM6 | O15303 | 3/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GRM8 | O00222 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6105605 | 0.82 | GRM4 (0.35) | GRM1GRM4CYP2C19CYP1A2GRM6 | |
| SCHEMBL11460947 | 0.81 | GRM1 (0.35) | GRM1GRM4CYP2C19CYP1A2GRM6 | |
| SCHEMBL27457235 | 0.76 | ALDH1A1 (0.35) | GRM1GRM4CYP2C19CYP1A2GRM6 | |
| SCHEMBL5203259 | 0.73 | CYP2C19 (0.35) | GRM1GRM4CYP2C19CYP1A2GRM6 | |
| SCHEMBL6686381 | 0.73 | CYP2C19 (0.35) | GRM1GRM4CYP2C19CYP1A2GRM6 | |
| SCHEMBL9058677 | 0.72 | GRM4 (0.58) | GRM1GRM4CYP2C19CYP1A2GRM6 | |
| SCHEMBL7140236 | 0.71 | GRM4 (0.56) | GRM1GRM4CYP2C19CYP1A2GRM6 | |
| SCHEMBL1661517 | 0.71 | GRM4 (0.33) | GRM1GRM4CYP2C19CYP1A2GRM6 | |
| SCHEMBL13529287 | 0.71 | GRM4 (0.39) | GRM1GRM4CYP2C19CYP1A2GRM6 | |
| SCHEMBL4650803 | 0.71 | CYP2D6 (0.35) | GRM1GRM4CYP2C19CYP1A2GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4149017-A | FERTILITY CONTROL, ANTIULCER AGENTS, BRONCHODILATOR, ANTICOAGULANT | MILES LABORATORIES, INC. (US) | 1979-04-10 | — | — | US | disclosed |
| US-4115438-A | SMOOTH MUSCLE ACTIVITY, ANTICLOTTING, ANTISECRETORY, BLOOD PRESSURE | MILES LABORATORIES, INC. (US) | 1978-09-19 | — | — | US | disclosed |
| US-4115453-A | SMOOTH MUSCLE ACTIVITY, ANTICOAGULANTS, ANTISECRETORY, HYPOTENSIVE | MILES LABORATORIES, INC. (US) | 1978-09-19 | — | — | US | disclosed |
| US-4108892-A | ANTICOAGULATNS, SMOOTH MUSCLE ACTIVITY MODIFIERS, ANTISECRETORY | MILES LABORATORIES, INC. (US) | 1978-08-22 | — | — | US | disclosed |