Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitroanilide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG known ✓ | P00747 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitroanilide SCHEMBL22394597 | 0.82 | ALDH1A1 (0.41) | KMT2AALDH1A1MEN1LMNAL3MBTL1 | |
| Aminocaproic Acid SCHEMBL28412351 | 0.80 | KMT2A (0.55) | KMT2AALDH1A1MEN1LMNATHRB | |
| Aminocaproic Acid SCHEMBL9746217 | 0.80 | LMNA (0.59) | KMT2AALDH1A1MEN1LMNATHRB | |
| Lysine SCHEMBL20303616 | 0.79 | GSR (0.54) | KMT2ATHRBTDP1MMP2LTA4H | |
| Lysine SCHEMBL20303617 | 0.79 | GSR (0.54) | KMT2ATHRBTDP1MMP2LTA4H | |
| Lysine SCHEMBL28468625 | 0.78 | GSR (0.53) | KMT2ATHRBTDP1MMP2LTA4H | |
| Hydrochloric Acid SCHEMBL8360213 | 0.77 | BLM (0.55) | KMT2AALDH1A1MEN1LMNATHRB | |
| Nitroanilide SCHEMBL30874122 | 0.77 | ALDH1A1 (0.47) | KMT2AALDH1A1MEN1LMNAL3MBTL1 | |
| Naphthalene SCHEMBL6898872 | 0.76 | LMNA (0.68) | KMT2AALDH1A1MEN1LMNATHRB | |
| Nitroanilide SCHEMBL29026133 | 0.75 | ALDH1A1 (0.46) | KMT2AALDH1A1MEN1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117757085-A | Sialic acid modified hypoxia response type chitosan nitrobenzene grafting material, preparation and application | 浙江大学 | 2024-03-26 | — | — | CN | claimed |
| CN-117757085-A | Sialic acid modified hypoxia response type chitosan nitrobenzene grafting material, preparation and application | 浙江大学 | 2024-03-26 | — | — | CN | disclosed |