Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570580 | 0.85 | CTSK (0.36) | GAACTSKMEN1KMT2AMAPK1 | |
| SCHEMBL571145 | 0.82 | CTSK (0.35) | GAACTSKMEN1KMT2AMAPK1 | |
| SCHEMBL2500185 | 0.82 | CTSK (0.35) | GAACTSKMEN1KMT2AMAPK1 | |
| SCHEMBL20338584 | 0.81 | P2RX7 (0.35) | GAACTSKMEN1KMT2AMAPK1 | |
| SCHEMBL2496562 | 0.81 | P2RX7 (0.35) | GAACTSKMEN1KMT2AMAPK1 | |
| SCHEMBL20338609 | 0.81 | P2RX7 (0.35) | GAACTSKMEN1KMT2AMAPK1 | |
| SCHEMBL23007977 | 0.80 | GAA (0.39) | GAACTSKMEN1KMT2AMAPK1 | |
| SCHEMBL25645220 | 0.79 | APLNR (0.36) | GAACTSKMEN1KMT2AMAPK1 | |
| SCHEMBL28607231 | 0.77 | CTSK (0.35) | GAACTSKMEN1KMT2AMAPK1 | |
| SCHEMBL24884855 | 0.73 | GAA (0.39) | GAACTSKMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767103-B | Novel spirocyclic K-Ras G12C inhibitors | 微境生物医药科技(上海)有限公司 | 2024-03-29 | — | — | CN | disclosed |