Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29727936 | 1.00 | LMNA (0.42) | LMNAMAPTGAAALDH1A1NPC1 | |
| SCHEMBL286932 | 0.76 | ALDH1A1 (0.37) | LMNAMAPTGAAALDH1A1NPC1 | |
| SCHEMBL29727938 | 0.75 | ALDH1A1 (0.41) | LMNAMAPTGAAALDH1A1NPC1 | |
| SCHEMBL30512980 | 0.72 | ALDH1A1 (0.39) | LMNAMAPTGAAALDH1A1NPC1 | |
| SCHEMBL29606965 | 0.71 | GAA (0.41) | LMNAMAPTGAAALDH1A1NPC1 | |
| SCHEMBL6858422 | 0.71 | ALDH1A1 (0.38) | LMNAMAPTGAAALDH1A1NPC1 | |
| SCHEMBL29727935 | 0.71 | ALDH1A1 (0.42) | LMNAMAPTGAAALDH1A1NPC1 | |
| SCHEMBL29727942 | 0.71 | TSHR (0.40) | LMNAMAPTGAAALDH1A1NPC1 | |
| SCHEMBL29558777 | 0.69 | ALDH1A1 (0.47) | LMNAMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL6585668 | 0.69 | ALDH1A1 (0.36) | LMNAMAPTGAAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114751899-B | Diaryl urea mTOR kinase inhibitor, and pharmaceutical composition and application thereof | 贵州医科大学 | 2024-03-29 | — | — | CN | disclosed |