Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29727938 | 0.82 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL15256933 | 0.76 | ALDH1A1 (0.50) | ALDH1A1NPC1CYP3A4GAALMNA | |
| SCHEMBL29727942 | 0.75 | TSHR (0.40) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL29727935 | 0.75 | ALDH1A1 (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL29606965 | 0.75 | GAA (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL29727936 | 0.72 | LMNA (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL29280577 | 0.72 | LMNA (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL6585668 | 0.72 | ALDH1A1 (0.36) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL6585665 | 0.72 | ALDH1A1 (0.36) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL6670418 | 0.71 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138612-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-27 | — | — | WO | disclosed |