Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.33 |
| ▸ | CDC25A | P30304 | 2/20 | 0.33 |
| ▸ | CDC25B | P30305 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28894956 | 1.00 | TSHR (0.54) | TSHRLMNAKMT2ATDP1HSD17B10 | |
| Succinic Acid SCHEMBL28916613 | 0.87 | LMNA (0.45) | TSHRLMNAKMT2AAPEX1ALDH1A1 | |
| Succinic Acid SCHEMBL722926 | 0.87 | LMNA (0.45) | TSHRLMNAKMT2AAPEX1ALDH1A1 | |
| Adipic Acid SCHEMBL906129 | 0.83 | LMNA (0.50) | TSHRLMNAKMT2AALDH1A1FOLH1 | |
| Adipic Acid SCHEMBL29427201 | 0.83 | LMNA (0.50) | TSHRLMNAKMT2AALDH1A1FOLH1 | |
| Glutarate SCHEMBL28487046 | 0.83 | SLC22A6 (0.50) | TSHRLMNAKMT2ACYP1A2MEN1 | |
| Glutarate SCHEMBL9485824 | 0.83 | SLC22A6 (0.50) | TSHRLMNAKMT2ACYP1A2MEN1 | |
| Octanedioate SCHEMBL6037661 | 0.81 | TSHR (0.52) | TSHRLMNAKMT2ATDP1HSD17B10 | |
| Succinic Acid SCHEMBL28778164 | 0.81 | LMNA (0.39) | TSHRLMNAKMT2AAPEX1ALDH1A1 | |
| Octanedioate SCHEMBL1394807 | 0.81 | TSHR (0.52) | TSHRLMNAKMT2ATDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777320-A | Low molecular weight heparin mimics based on heparin pentasaccharide and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-03-29 | — | — | CN | disclosed |