Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19503120 | 0.80 | TLR7 (0.49) | KMT2APDE1BALDH1A1TLR7MEN1 | |
| SCHEMBL20475953 | 0.77 | MMP1 (0.43) | PIK3R1PIK3CAPDE1BMAPK8TLR7 | |
| SCHEMBL20741495 | 0.77 | KCNH2 (0.44) | PIK3R1PIK3CAMAPTPDE1BSMN1; SMN2 | |
| SCHEMBL20475942 | 0.77 | TSPO (0.42) | PIK3R1PIK3CAPDE1BMAPK8TLR7 | |
| SCHEMBL30842223 | 0.77 | TSPO (0.42) | PIK3R1PIK3CAPDE1BMAPK8TLR7 | |
| SCHEMBL30842213 | 0.77 | KCNH2 (0.44) | PIK3R1PIK3CAMAPTPDE1BSMN1; SMN2 | |
| SCHEMBL19475350 | 0.77 | TLR7 (0.46) | MAPTKMT2ASMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL20475954 | 0.77 | MAPK8 (0.39) | PIK3R1PIK3CAMAPTKMT2APDE1B | |
| SCHEMBL21949797 | 0.74 | TSPO (0.39) | PIK3R1PIK3CAKMT2APDE1BMAPK8 | |
| SCHEMBL29920814 | 0.74 | TSPO (0.39) | PIK3R1PIK3CAKMT2APDE1BMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325534-B | Substituted imidazoquinolines as NLRP3 modulators | 先天肿瘤免疫公司 | 2024-04-05 | — | — | CN | disclosed |