Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 16/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 14/20 | 0.46 |
| ▸ | PPARG | P37231 | 9/20 | 0.44 |
| ▸ | PTGES | O14684 | 7/20 | 0.44 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2934881 | 0.87 | APP (0.48) | TACR2 | |
| SCHEMBL2932073 | 0.83 | APP (0.49) | TACR2 | |
| SCHEMBL7187849 | 0.82 | MRGPRX4 (0.50) | PSEN1ALOX5PPARGPTGES | |
| SCHEMBL2930191 | 0.80 | RXRA (0.54) | PSEN1ALOX5RXRARXRBRXRG | |
| SCHEMBL2928136 | 0.79 | APP (0.47) | — | |
| SCHEMBL2931922 | 0.79 | RXRA (0.47) | PSEN1ALOX5TACR2RXRARXRB | |
| SCHEMBL2931028 | 0.79 | ALDH1A1 (0.49) | PPARG | |
| SCHEMBL2928050 | 0.78 | ALDH1A1 (0.49) | — | |
| SCHEMBL2932518 | 0.77 | CYP2C9 (0.47) | ALOX5PPARGPTGES | |
| SCHEMBL856842 | 0.73 | ALDH1A1 (0.60) | TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313731-B1 | THIAZOLIDINE DERIVATIVES AND ITS USE AS ANTIFUNGAL AGENT | UCB SA (BE) | 2010-09-29 | — | — | EP | disclosed |
| EP-1313731-B1 | THIAZOLIDINE DERIVATIVES AND ITS USE AS ANTIFUNGAL AGENT | UCB SA (BE) | 2010-09-29 | — | — | EP | disclosed |
| US-6740670-B2 | SUCH AS 5-(((3-(N-METHYL-N-PHENYLAMINO)CARBONYL-4-(PHENYL-METHOXY)) -PHENYL)METHYLENE)-4-OXO-2-THIOXO-3-THIAZOLIDINE-ACETIC ACID | OXFORD GLYCOSCIENCES (UK) LTD. (GB) | 2004-05-25 | — | — | US | disclosed |
| US-20030216453-A1 | Thiazolidine derivatives and its use as antifungal agent | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2003-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216453-A1 | Thiazolidine derivatives and its use as antifungal agent | CYP3A7, TAS2R7, OXSR1 | PSEN1 4321/4885ALOX5 3986/4885PPARG 3127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.