Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 10/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30843799 | 0.88 | ERN1 (0.57) | ERN1MAOBTLR2TLR1TLR6 | |
| SCHEMBL1125310 | 0.88 | ERN1 (0.57) | ERN1MAOBTLR2TLR1TLR6 | |
| SCHEMBL30313045 | 0.71 | MAOB (0.45) | MAOBPOLBGRIN1GRIN2B | |
| SCHEMBL173039 | 0.71 | ALOX12 (0.62) | ERN1TLR2TLR1TLR6TRIM24 | |
| SCHEMBL22278289 | 0.71 | ERN1 (0.55) | ERN1TLR2TLR1TLR6TRIM24 | |
| SCHEMBL458508 | 0.71 | PIM1 (0.42) | ERN1MAOBNFKB1PIM1PIM3 | |
| SCHEMBL31587806 | 0.71 | ALOX12 (0.62) | ERN1TLR2TLR1TLR6TRIM24 | |
| SCHEMBL7031301 | 0.71 | NFKB1 (0.42) | ERN1MAOBNFKB1MAPTBACE1 | |
| SCHEMBL6853771 | 0.70 | NFKB1 (0.44) | ERN1MAOBNFKB1PIM1PIM3 | |
| SCHEMBL22083591 | 0.70 | ERN1 (0.47) | ERN1MAOBTLR2TLR1TLR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820164-A | Bis 3- (trifluoromethyl) salicylaldehyde 1, 4-xylylenediamine Schiff base, and preparation method and application thereof | 安徽省东超科技有限公司 | 2024-04-05 | — | — | CN | disclosed |