Sugi Predict

Sugi Predict / Compounds / Ethopabate

Ethopabate

Ethopabate

SCHEMBL540932

CCOc1cc(NC(C)=O)ccc1C(=O)OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 4/20 1.00
▸ SMN1; SMN2 Q16637 1/20 0.61
▸ RORC P51449 1/20 0.61
▸ KMT2A Q03164 4/20 0.58
▸ MEN1 O00255 3/20 0.58
▸ LMNA P02545 1/20 0.58
▸ CYP1A2 P05177 1/20 0.58
▸ MAPT P10636 5/20 0.54
▸ CDK1 P06493 1/20 0.54
▸ POLB P06746 1/20 0.49
▸ RAB9A P51151 1/20 0.48
▸ KDM4E B2RXH2 4/20 0.47
▸ CREBBP Q92793 1/20 0.46
▸ ALDH1A1 P00352 3/20 0.45
▸ GAA P10253 2/20 0.45
▸ CYP3A4 P08684 1/20 0.45
▸ TSHR P16473 1/20 0.45
▸ KCNK3 O14649 1/20 0.45
▸ KCNK9 Q9NPC2 1/20 0.45
▸ HPGD P15428 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethopabate SCHEMBL29625103 1.00 TDP1 (1.00) TDP1SMN1; SMN2RORCKMT2AMEN1
Ethopabate SCHEMBL28629644 0.99 TDP1 (0.97) TDP1SMN1; SMN2RORCKMT2AMEN1
SCHEMBL21219501 0.90 TDP1 (0.82) TDP1SMN1; SMN2RORCKMT2AMEN1
SCHEMBL28427762 0.89 TDP1 (0.80) TDP1SMN1; SMN2RORCKMT2AMEN1
SCHEMBL7371976 0.87 TDP1 (0.76) TDP1SMN1; SMN2RORCKMT2AMEN1
SCHEMBL7367372 0.85 TDP1 (0.74) TDP1SMN1; SMN2RORCKMT2AMEN1
SCHEMBL8687307 0.85 TDP1 (0.73) TDP1SMN1; SMN2RORCKMT2AMEN1
SCHEMBL2555975 0.84 TDP1 (0.73) TDP1SMN1; SMN2KMT2AMEN1LMNA
Ethyl Acetate SCHEMBL29281111 0.83 TDP1 (0.71) TDP1SMN1; SMN2RORCKMT2AMEN1
SCHEMBL7326428 0.83 TDP1 (0.71) TDP1SMN1; SMN2RORCKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 490 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111060638-B Screening and confirming method for 207 veterinary drugs and additives in animal food 河南省兽药饲料监察所(河南省畜产品质量监测检验中心) 2022-06-03 — — CN claimed
CN-114311769-A Method for producing ton bag 青铜峡市华峰塑胶有限公司 2022-04-12 — — CN claimed
US-11246836-B2 Intramuscular depot of decoquinate compositions and method of prophylaxis and treatment thereof BLUELIGHT PHARMATECH CO., LTD. (CN) 2022-02-15 — — US claimed
CN-113117719-A Nickel-based metal nano material with unconventional crystalline phase and preparation method and application thereof 中山大学 2021-07-16 — — CN claimed
CN-108715729-B Preparation method of flame-retardant antibacterial waterborne polyurethane coating and adhesive 浙江伟涛包装材料有限公司 2021-06-08 — — CN claimed
US-20210063375-A1 SCREENING AND CONFIRMATION METHOD FOR VETERINARY DRUGS AND ADDITIVES IN ANIMAL-DERIVED FOOD HENAN INST OF VETERINARY DRUG AND FEED CONTROL (CN) 2021-03-04 — — US claimed
US-20210059946-A1 INTRAMUSCULAR DEPOT OF DECOQUINATE COMPOSITIONS AND METHOD OF PROPHYLAXIS AND TREATMENT THEREOF CAS LAMVAC (GUANGZHOU) BIOMEDICAL TECHNOLOGY CO., LTD. (CN) 2021-03-04 — — US claimed
CN-111060638-A Screening and confirming method for 207 veterinary drugs and additives in animal food 河南省兽药饲料监察所(河南省畜产品质量监测检验中心) 2020-04-24 — — CN claimed
WO-2019218305-A1 INTRAMUSCULAR DEPOT OF DECOQUINATE COMPOSITIONS AND METHOD OF PROPHYLAXIS AND TREATMENT THEREOF Bluelight Pharmatech Co., Ltd (CN) 2019-11-21 — — WO claimed
CN-109761944-A A kind of chrysin amide derivatives and preparation method thereof and medical usage 武汉翼博济生生物科技有限公司 2019-05-17 — — CN claimed
US-5646135-A ADMINISTERING, IN SEQUENCE, TWO DIFFERENT ANTICOCCIDIAL COMPOUNDS TO POULTRY MERCK & CO., INC. (US) 1997-07-08 — — US claimed
WO-1996038140-A1 AGENTS FOR USE AGAINST PARASITIC PROTOZOA BAYER AKTIENGESELLSCHAFT (DE) 1996-12-05 — — WO claimed
EP-0268135-B1 COCCIDIOCIDAL AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1992-12-16 — — EP claimed
EP-0246532-B1 COCCIDIOCIDAL AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-01 — — EP claimed
US-4861758-A Coccidiocidal compositions HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-29 — — US claimed
US-4824847-A SYNERGISTIC MIXTURE CONTAINING LASALOCID A HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-25 — — US claimed
EP-0279290-A2 Anticoccidial agent HOECHST AKTIENGESELLSCHAFT (DE) 1988-08-24 — — EP claimed
EP-0268135-A2 Coccidiocidal agents HOECHST AKTIENGESELLSCHAFT (DE) 1988-05-25 — — EP claimed
EP-0267520-A2 Coccidiocidal agents HOECHST AKTIENGESELLSCHAFT (DE) 1988-05-18 — — EP claimed
EP-0246532-A1 Coccidiocidal agents HOECHST AKTIENGESELLSCHAFT (DE) 1987-11-25 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210059946-A1 INTRAMUSCULAR DEPOT OF DECOQUINATE COMPOSITIONS AND METHOD OF PROPHYLAXIS AND TREATMENT THEREOF HMGCR, DECR1, GYS1 TDP1 2283/4885SMN1; SMN2 3942/4885RORC 728/4885
US-11246836-B2 Intramuscular depot of decoquinate compositions and method of prophylaxis and treatment thereof HMGCR, DECR1, GYS1 TDP1 2283/4885SMN1; SMN2 3942/4885RORC 728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.