Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.32 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.32 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30262354 | 1.00 | CA2 (0.37) | CA2LPLLIPGHDAC4CES2 | |
| SCHEMBL6588524 | 0.83 | CA2 (0.33) | CA2LPLLIPG | |
| SCHEMBL29604796 | 0.83 | CA2 (0.33) | CA2LPLLIPG | |
| SCHEMBL29465765 | 0.81 | CA2 (0.32) | CA2LPLLIPG | |
| SCHEMBL5917526 | 0.81 | CA2 (0.37) | CA2LPLLIPGORAI1ORAI2 | |
| SCHEMBL18287667 | 0.81 | CA2 (0.32) | CA2LPLLIPG | |
| SCHEMBL59883 | 0.80 | CES2 (0.41) | LPLLIPGCES2CES1 | |
| SCHEMBL29465762 | 0.80 | CES2 (0.41) | LPLLIPGCES2CES1 | |
| SCHEMBL25116004 | 0.79 | ENPP2 (0.36) | CES2CES1 | |
| SCHEMBL19171723 | 0.79 | ERN1 (0.38) | CA2LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858875-A | Hydroxy-and (halo) alkoxy-substituted tetrahydrofurans as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2024-04-09 | — | — | CN | disclosed |