Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2929421 | 0.91 | KDM4E (0.54) | KDM4EALDH1A1POLBL3MBTL1TSHR | |
| SCHEMBL6811278 | 0.89 | KDM4E (0.46) | KDM4EALDH1A1POLBL3MBTL1TSHR | |
| SCHEMBL2930961 | 0.82 | TSHR (0.52) | KDM4EALDH1A1POLBL3MBTL1TSHR | |
| SCHEMBL2928136 | 0.81 | APP (0.47) | KDM4EALDH1A1POLBL3MBTL1APP | |
| SCHEMBL2926924 | 0.80 | PTGER1 (0.51) | KDM4EALDH1A1POLBL3MBTL1TSHR | |
| SCHEMBL2932095 | 0.79 | PDK1 (0.51) | KDM4EALDH1A1POLBL3MBTL1MAOA | |
| SCHEMBL2933284 | 0.78 | TSHR (0.46) | KDM4EALDH1A1TSHRMAOAMAOB | |
| SCHEMBL2932073 | 0.78 | APP (0.49) | KDM4EALDH1A1POLBL3MBTL1MAOA | |
| SCHEMBL6805058 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1POLBL3MBTL1MAOA | |
| SCHEMBL2932209 | 0.77 | MAOA (0.57) | KDM4EALDH1A1POLBL3MBTL1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313731-B1 | THIAZOLIDINE DERIVATIVES AND ITS USE AS ANTIFUNGAL AGENT | UCB SA (BE) | 2010-09-29 | — | — | EP | disclosed |
| US-6740670-B2 | SUCH AS 5-(((3-(N-METHYL-N-PHENYLAMINO)CARBONYL-4-(PHENYL-METHOXY)) -PHENYL)METHYLENE)-4-OXO-2-THIOXO-3-THIAZOLIDINE-ACETIC ACID | OXFORD GLYCOSCIENCES (UK) LTD. (GB) | 2004-05-25 | — | — | US | disclosed |
| US-20030216453-A1 | Thiazolidine derivatives and its use as antifungal agent | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2003-11-20 | — | — | US | disclosed |
| EP-1313731-A1 | THIAZOLIDINE DERIVATIVES AND ITS USE AS ANTIFUNGAL AGENT | Oxford GlycoSciences (UK) Limited (GB) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002022612-A1 | THIAZOLIDINE DERIVATIVES AND ITS USE AS ANTIFUNGAL AGENT | OXFORD GLYCOSCIENCES (UK) LIMITED (GB) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216453-A1 | Thiazolidine derivatives and its use as antifungal agent | CYP3A7, TAS2R7, OXSR1 | KDM4E 3752/4885ALDH1A1 2527/4885POLB 4579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.