SCHEMBL2928156

SCHEMBL2928156

CCCCCCCCP(CCCCCCCC)C(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
THRB P10828 1/20 0.44
DNM1 Q05193 8/20 0.38
ALDH1A1 P00352 3/20 0.35
LMNA P02545 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HSD17B10 Q99714 1/20 0.35
SLC22A1 O15245 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2921614 1.00 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
Bromide SCHEMBL6698556 0.95 TSHR (0.40) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL2925543 0.88 TSHR (0.35) TSHRTHRBALDH1A1LMNA
Bromide SCHEMBL6697842 0.87 TSHR (0.38) TSHRTHRBDNM1ALDH1A1LMNA
Bromide SCHEMBL6702789 0.83 TSHR (0.32) TSHRTHRBLMNA
SCHEMBL2925546 0.79 TSHR (0.40) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL2925926 0.79 TSHR (0.40) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL2931479 0.78 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL700161 0.78 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL15657069 0.76 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113631545-B Polyisocyanurate materials as electrical potting compounds 科思创德国股份有限公司 2025-01-07 CN disclosed
CN-112204065-B Process for preparing polyisocyanate polymers and polyisocyanurate plastics 科思创知识产权两合公司 2023-03-28 CN disclosed
CN-109642015-B Method for producing polyisocyanurate plastics by means of phosphine catalysis 科思创德国股份有限公司 2022-09-23 CN disclosed
EP-3794049-B1 METHOD FOR PRODUCING A POLYISOCYANATE POLYMER AND A POLYISOCYANURATE PLASTIC COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-06-08 EP disclosed
US-11319402-B2 Method for producing a polyisocyanate polymer and a polyisocyanurate plastic COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2022-05-03 US disclosed
US-20220127407-A1 POLYISOCYANURATE MATERIALS AS ELECTRICAL POTTING COMPOUNDS COVESTRO DEUTSCHLAND AG (DE) 2022-04-28 US disclosed
EP-3931185-A1 POLYISOCYANURATE MATERIALS AS ELECTRICAL POTTING COMPOUNDS Covestro Intellectual Property GmbH & Co. KG (DE) 2022-01-05 EP disclosed
CN-113631545-A Polyisocyanurate materials as electrical potting compounds 科思创知识产权两合公司 2021-11-09 CN disclosed
US-20210246255-A1 METHOD FOR PRODUCING A POLYISOCYANATE POLYMER AND A POLYISOCYANURATE PLASTIC COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-08-12 US disclosed
CN-113166364-A Method for producing composite materials from polyethylene fibres having an ultrahigh molecular weight and crosslinked polyisocyanates 科思创知识产权两合公司 2021-07-23 CN disclosed
EP-3794049-A1 METHOD FOR PRODUCING A POLYISOCYANATE POLYMER AND A POLYISOCYANURATE PLASTIC Covestro Intellectual Property GmbH & Co. KG (DE) 2021-03-24 EP disclosed
CN-112204065-A Process for preparing polyisocyanate polymers and polyisocyanurate plastics 科思创知识产权两合公司 2021-01-08 CN disclosed
EP-3507321-A1 PROCESS FOR PRODUCING POLYISOCYANURATE PLASTICS BY MEANS OF PHOSPHINE CATALYSIS Covestro Deutschland AG (DE) 2019-07-10 EP disclosed
US-20190202963-A1 PROCESS FOR PRODUCING POLYISOCYANURATE PLASTICS BY MEANS OF PHOSPHINE CATALYSIS COVESTRO DEUTSCHLAND AG (DE) 2019-07-04 US disclosed
CN-109642015-A Method for producing polyisocyanurate plastics by means of phosphine catalysis 科思创德国股份有限公司 2019-04-16 CN disclosed
WO-2018041800-A1 PROCESS FOR PRODUCING POLYISOCYANURATE PLASTICS BY MEANS OF PHOSPHINE CATALYSIS COVESTRO DEUTSCHLAND AG (DE) 2018-03-08 WO disclosed
US-7709680-B2 Preparation of polyisocyanates containing uretdione groups using phosphine catalysts BAYER MATERIALSCIENCE AG (DE) 2010-05-04 US disclosed
EP-1982979-B1 Manufacture of polyisocyanates containing uretdione groups BAYER MATERIALSCIENCE AG (DE) 2010-01-27 EP disclosed
US-20080262262-A1 Preparation of polyisocyanates containing uretdione groups using phosphine catalysts BAYER MATERIALSCIENCE AG 2008-10-23 US disclosed
EP-1982979-A1 Manufacture of polyisocyanates containing uretdione groups Bayer MaterialScience AG (DE) 2008-10-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080262262-A1 Preparation of polyisocyanates containing uretdione groups using phosphine catalysts PPIP5K2, IPMK, INPP5B TSHR 4316/4885THRB 4743/4885DNM1 3080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.