Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700161 | 1.00 | TSHR (0.44) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL705678 | 0.97 | TSHR (0.42) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL2349410 | 0.97 | TSHR (0.39) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL17287830 | 0.92 | TSHR (0.35) | TSHRTHRBDNM1LMNA | |
| SCHEMBL31418370 | 0.91 | TSHR (0.36) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL301833 | 0.88 | TSHR (0.35) | TSHRTHRBLMNA | |
| SCHEMBL2925932 | 0.79 | TSHR (0.40) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL2928156 | 0.78 | TSHR (0.44) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL2921614 | 0.78 | TSHR (0.44) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL2168149 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204065-B | Process for preparing polyisocyanate polymers and polyisocyanurate plastics | 科思创知识产权两合公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-109642015-B | Method for producing polyisocyanurate plastics by means of phosphine catalysis | 科思创德国股份有限公司 | 2022-09-23 | — | — | CN | disclosed |
| EP-3794049-B1 | METHOD FOR PRODUCING A POLYISOCYANATE POLYMER AND A POLYISOCYANURATE PLASTIC | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2022-06-08 | — | — | EP | disclosed |
| CN-114555615-A | Complexes | 庄信万丰股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| US-11319402-B2 | Method for producing a polyisocyanate polymer and a polyisocyanurate plastic | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2022-05-03 | — | — | US | disclosed |
| US-20220127407-A1 | POLYISOCYANURATE MATERIALS AS ELECTRICAL POTTING COMPOUNDS | COVESTRO DEUTSCHLAND AG (DE) | 2022-04-28 | — | — | US | disclosed |
| EP-3931185-A1 | POLYISOCYANURATE MATERIALS AS ELECTRICAL POTTING COMPOUNDS | Covestro Intellectual Property GmbH & Co. KG (DE) | 2022-01-05 | — | — | EP | disclosed |
| CN-113631545-A | Polyisocyanurate materials as electrical potting compounds | 科思创知识产权两合公司 | 2021-11-09 | — | — | CN | disclosed |
| US-20210246255-A1 | METHOD FOR PRODUCING A POLYISOCYANATE POLYMER AND A POLYISOCYANURATE PLASTIC | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2021-08-12 | — | — | US | disclosed |
| CN-113166364-A | Method for producing composite materials from polyethylene fibres having an ultrahigh molecular weight and crosslinked polyisocyanates | 科思创知识产权两合公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-109642015-A | Method for producing polyisocyanurate plastics by means of phosphine catalysis | 科思创德国股份有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-106488920-A | The preparation method of antiviral compound | 吉利德制药有限责任公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-101289427-B | Preparation of polyisocyanates containing uretdione groups using phosphine catalysts | BAYER MATERIALSCIENCE AG | 2012-06-06 | — | — | CN | disclosed |
| US-7709680-B2 | Preparation of polyisocyanates containing uretdione groups using phosphine catalysts | BAYER MATERIALSCIENCE AG (DE) | 2010-05-04 | — | — | US | disclosed |
| EP-1982979-B1 | Manufacture of polyisocyanates containing uretdione groups | BAYER MATERIALSCIENCE AG (DE) | 2010-01-27 | — | — | EP | disclosed |
| US-20080262262-A1 | Preparation of polyisocyanates containing uretdione groups using phosphine catalysts | BAYER MATERIALSCIENCE AG | 2008-10-23 | — | — | US | disclosed |
| EP-1982979-A1 | Manufacture of polyisocyanates containing uretdione groups | Bayer MaterialScience AG (DE) | 2008-10-22 | — | — | EP | disclosed |
| CN-101289427-A | Preparation of polyisocyanates containing uretdione groups using phosphine catalysts | BAYER MATERIALSCIENCE AG (DE) | 2008-10-22 | — | — | CN | disclosed |
| EP-1282629-A1 | BIDENTATE LIGANDS USEFUL IN CATALYST SYTEMS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001087899-A1 | BIDENTATE LIGANDS USEFUL IN CATALYST SYSTEM | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2001-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262262-A1 | Preparation of polyisocyanates containing uretdione groups using phosphine catalysts | PPIP5K2, IPMK, INPP5B | TSHR 4316/4885THRB 4743/4885DNM1 3080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.