Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30913192 | 1.00 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3HCAR3HCAR2 | |
| SCHEMBL30913193 | 1.00 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3HCAR3HCAR2 | |
| SCHEMBL25975342 | 0.77 | OPRM1 (0.42) | OPRM1DRD4 | |
| SCHEMBL9966015 | 0.77 | OPRM1 (0.48) | OPRD1SIGMAR1OPRM1OPRK1OPRL1 | |
| SCHEMBL22646520 | 0.76 | OPRD1 (0.55) | SLC6A4SLC6A2SLC6A3OPRD1OPRM1 | |
| SCHEMBL15020188 | 0.74 | NR4A2 (0.39) | SLC6A4SLC6A2SLC6A3HCAR3HCAR2 | |
| SCHEMBL21064446 | 0.72 | OPRM1 (0.39) | SLC6A4SLC6A2SLC6A3OPRD1OPRM1 | |
| SCHEMBL28256063 | 0.69 | OPRM1 (0.46) | OPRD1SIGMAR1OPRM1OPRK1OPRL1 | |
| SCHEMBL10323222 | 0.69 | PDE2A (0.35) | HCAR3HCAR2 | |
| SCHEMBL21241861 | 0.68 | OPRM1 (0.36) | SLC6A4SLC6A2SLC6A3OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986241-A | Biphenyl derivative, pharmaceutical composition and application thereof | 武汉睿健医药科技有限公司 | 2024-05-07 | — | — | CN | disclosed |