SCHEMBL29282133

SCHEMBL29282133

CCNC(=O)CCc1cccc(Cl)c1

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
KMT2A Q03164 4/20 0.61
SMN1; SMN2 Q16637 3/20 0.58
HPGD P15428 3/20 0.55
MEN1 O00255 1/20 0.55
PLAAT3 P53816 2/20 0.55
PLAAT5 Q96KN8 2/20 0.55
PLAAT2 Q9NWW9 2/20 0.55
PLAAT4 Q9UL19 2/20 0.55
TAAR1 Q96RJ0 2/20 0.50
TSHR P16473 1/20 0.50
CSNK1D P48730 1/20 0.50
RXFP1 Q9HBX9 1/20 0.49
MAPT P10636 1/20 0.49
CNR1 P21554 1/20 0.49
PYGL P06737 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30913196 1.00 ALDH1A1 (0.61) ALDH1A1KMT2ASMN1; SMN2HPGDMEN1
SCHEMBL14233695 0.85 HPGD (0.54) ALDH1A1HPGDMAPT
SCHEMBL5038560 0.85 MAOB (0.58)
SCHEMBL29481931 0.84 MEN1 (0.61) ALDH1A1KMT2ASMN1; SMN2HPGDMEN1
SCHEMBL17151448 0.84 MEN1 (0.61) ALDH1A1KMT2ASMN1; SMN2HPGDMEN1
SCHEMBL6195881 0.80 PLAAT3 (0.71) ALDH1A1KMT2AHPGDMEN1PLAAT3
SCHEMBL14559555 0.80 CNR1 (0.66) ALDH1A1KMT2ASMN1; SMN2HPGDMEN1
SCHEMBL2524341 0.80 HPGD (0.68) ALDH1A1KMT2AHPGDMEN1MAPT
SCHEMBL1848 0.78 ALDH1A1 (0.60) ALDH1A1KMT2ASMN1; SMN2HPGDMEN1
SCHEMBL14241870 0.78 ALDH1A1 (0.71) ALDH1A1KMT2ASMN1; SMN2HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117986241-A Biphenyl derivative, pharmaceutical composition and application thereof 武汉睿健医药科技有限公司 2024-05-07 CN disclosed