Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.56 |
| ▸ | RXRB | P28702 | 1/20 | 0.56 |
| ▸ | RXRG | P48443 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30913196 | 0.85 | ALDH1A1 (0.61) | — | |
| SCHEMBL29282133 | 0.85 | ALDH1A1 (0.61) | — | |
| SCHEMBL9626424 | 0.84 | MAOB (0.69) | MAOBMAOAALOX5RXRARXRB | |
| SCHEMBL8935322 | 0.80 | GID4 (0.71) | MAOBMAOAGID4ALOX5RXRA | |
| SCHEMBL8935287 | 0.79 | MAOB (0.64) | MAOBMAOAALOX5RXRARXRB | |
| SCHEMBL1746764 | 0.78 | FFAR1 (0.61) | MAOBMAOAALOX5RXRARXRB | |
| SCHEMBL9628272 | 0.77 | MAOB (0.60) | MAOBMAOAGID4ALOX5RXRA | |
| SCHEMBL8935243 | 0.77 | GID4 (0.74) | MAOBMAOAGID4ALOX5RXRA | |
| SCHEMBL9628508 | 0.76 | MAOB (0.71) | MAOBMAOAALOX5RXRARXRB | |
| SCHEMBL4417319 | 0.76 | MAOB (0.73) | MAOBMAOAALOX5RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1523469-B1 | CINNAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-10-08 | — | — | EP | claimed |
| EP-1523469-B1 | CINNAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-10-08 | — | — | EP | disclosed |
| EP-0477184-A1 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INDUSTRIE ET SANTE (FR) | 1992-04-01 | — | — | EP | disclosed |
| WO-1990011997-A2 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-18 | — | — | WO | disclosed |