SCHEMBL29282921

SCHEMBL29282921

CC(C)(C)c1ccc(C(CBr)O[N+](=O)[O-])cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.44
CNR1 P21554 1/20 0.36
LMNA P02545 3/20 0.35
GRIA4 P48058 3/20 0.35
ATM Q13315 1/20 0.34
GPR35 Q9HC97 1/20 0.34
SLC6A9 P48067 2/20 0.33
UTS2R Q9UKP6 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
NR1H4 Q96RI1 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8957482 0.71 GRIA4 (0.40) CNR1LMNAGRIA4ATMGPR35
SCHEMBL5608985 0.67 GRIA4 (0.41) CNR1LMNAGRIA4ATMGPR35
SCHEMBL17466740 0.67 GRIA4 (0.49) CNR1LMNAGRIA4ATMGPR35
SCHEMBL30943788 0.66 TSHR (0.41) LMNAGRIA4ATMGPR35ALDH1A1
SCHEMBL31229381 0.65 CA1 (0.46) LMNASMN1; SMN2CRHBPCRHR2ALDH1A1
SCHEMBL28462836 0.65 ALDH1A1 (0.47) LMNAALDH1A1MAPTMEN1KMT2A
SCHEMBL27319378 0.65 GSR (0.69) GSRLMNAALDH1A1MEN1KMT2A
SCHEMBL15929169 0.65 MAPT (0.47) LMNASMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL18253205 0.64 GRIA4 (0.41) LMNAGRIA4ATMGPR35UTS2R
SCHEMBL11492811 0.64 GRIA4 (0.41) LMNAGRIA4ATMGPR35NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063323-A Beta-halogenated nitrate compound and preparation method and application thereof 上海师范大学 2024-05-24 CN disclosed