SCHEMBL5608985

SCHEMBL5608985

CC(c1ccc(C(C)(C)C)cc1)[N+](=O)[O-]

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GRIA4 P48058 3/20 0.41
ALDH1A1 P00352 2/20 0.39
NPBWR1 P48145 1/20 0.39
NR1H4 Q96RI1 2/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
LMNA P02545 3/20 0.38
CNR1 P21554 1/20 0.38
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PDE2A O00408 1/20 0.37
TYR P14679 1/20 0.37
ATM Q13315 1/20 0.36
GPR35 Q9HC97 1/20 0.36
KIF11 P52732 1/20 0.36
FFAR1 O14842 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL265288 0.82 FBP1 (0.44) AKR1C3AKR1C2PDE2AKIF11FFAR1
SCHEMBL11745488 0.78 LMNA (0.41) GRIA4ALDH1A1NR1H4AKR1C3AKR1C2
SCHEMBL17018447 0.77 ACHE (0.48) GRIA4ALDH1A1LMNATSHRSMN1; SMN2
SCHEMBL17466740 0.76 GRIA4 (0.49) GRIA4ALDH1A1NR1H4LMNACNR1
SCHEMBL27496184 0.75 HSD17B10 (0.52) ALDH1A1LMNATSHR
SCHEMBL4087041 0.75 ALDH1A1 (0.46) GRIA4ALDH1A1LMNATSHRTP53
SCHEMBL12983360 0.75 CYP1A2 (0.39) ALDH1A1LMNATSHRSMN1; SMN2
SCHEMBL4543337 0.75 ESR1 (0.50) LMNA
SCHEMBL264810 0.75 ADRB2 (0.46) ALDH1A1LMNATSHRTP53
SCHEMBL18632149 0.75 L3MBTL1 (0.41) ALDH1A1SMN1; SMN2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112961093-A Method for reducing C = C double bond of nitroolefin with high selectivity 北京化工大学 2021-06-15 CN disclosed
EP-1354887-B1 Ligands for metals and improved metal-catalyzed processes based thereon MASSACHUSETTS INST TECHNOLOGY (US) 2007-04-25 EP disclosed
EP-1097158-B1 LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES MASSACHUSETTS INST TECHNOLOGY (US) 2006-01-25 EP disclosed
EP-1354887-A1 Ligands for metals and improved metal-catalyzed processes based thereon Massachusetts Insitute of Technology (US) 2003-10-22 EP disclosed
EP-1097158-A2 LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2001-05-09 EP disclosed
WO-2000002887-A2 LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2000-01-20 WO disclosed