SCHEMBL29282942

SCHEMBL29282942

CCCCO[PH](=O)CCc1ccc(C)cc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
CYP2A6 P11509 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
KCNH2 Q12809 3/20 0.36
HPGD P15428 2/20 0.36
CNR2 P34972 1/20 0.36
HTR2A P28223 1/20 0.36
THRB P10828 1/20 0.35
PTGES O14684 1/20 0.34
ALOX5 P09917 1/20 0.34
PPARG P37231 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HSD17B10 Q99714 1/20 0.34
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
DRD3 P35462 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19974057 0.87 CYP1A2 (0.40) CYP1A2CYP2A6TAAR1KCNH2HPGD
SCHEMBL29282941 0.83 CYP1A2 (0.45) CYP1A2CYP2A6TAAR1KCNH2ALDH1A1
SCHEMBL19974347 0.76 CYP1A2 (0.45) CYP1A2CYP2A6TAAR1KCNH2ALDH1A1
SCHEMBL23878218 0.73 LMNA (0.35) CYP1A2HPGDPTGESALOX5PPARG
SCHEMBL970082 0.72 CYP3A4 (0.37) HPGDALDH1A1
SCHEMBL1725405 0.72 CYP3A4 (0.37) HPGDALDH1A1
SCHEMBL19974058 0.72 SIGMAR1 (0.41) HPGDPTGESALOX5PPARG
SCHEMBL13639151 0.72 KCNH2 (0.58) CYP1A2CYP2A6TAAR1KCNH2ALDH1A1
SCHEMBL7740055 0.70 CYP3A4 (0.36) HPGDALDH1A1
SCHEMBL29151194 0.70 CYP3A4 (0.36) HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063856-A Flame retardant mixtures 科莱恩国际有限公司 2024-05-24 CN claimed
CN-118063856-A Flame retardant mixtures 科莱恩国际有限公司 2024-05-24 CN disclosed