Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25028482 | 0.80 | HDAC1 (0.41) | HDAC1HDAC4HDAC6HDAC3HDAC2 | |
| SCHEMBL25030170 | 0.75 | SIGMAR1 (0.38) | HDAC1HDAC4HDAC6POLBRAB9A | |
| SCHEMBL30233881 | 0.75 | SIGMAR1 (0.38) | HDAC1HDAC4HDAC6POLBRAB9A | |
| SCHEMBL16090969 | 0.74 | ALDH1A1 (0.50) | HDAC1HDAC4HDAC6HDAC3HDAC2 | |
| SCHEMBL30233983 | 0.73 | TSHR (0.39) | HDAC1HDAC4HDAC6HDAC3HDAC2 | |
| SCHEMBL25030421 | 0.73 | TSHR (0.39) | HDAC1HDAC4HDAC6HDAC3HDAC2 | |
| SCHEMBL27311606 | 0.72 | RAB9A (0.44) | POLBRAB9A | |
| SCHEMBL22151652 | 0.70 | MAPT (0.46) | POLBRAB9ATSHRALDH1A1 | |
| SCHEMBL31637826 | 0.70 | MAPT (0.46) | POLBRAB9ATSHRALDH1A1 | |
| SCHEMBL9941822 | 0.70 | TSHR (0.42) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103074-A | Cytotoxic targeting chimeras for CCR2 expressing cells | 葛兰素史克知识产权发展有限公司 | 2024-05-28 | — | — | CN | disclosed |