Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.54 |
| ▸ | GRM6 | O15303 | 1/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.54 |
| ▸ | GSR | P00390 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.54 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.54 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15124709 | 1.00 | GRM8 (0.54) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL4305231 | 0.85 | CYP1A2 (0.71) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL25384088 | 0.85 | CYP1A2 (0.71) | GRM8GRM6GRIN2DGRIN3BGSR | |
| D-Glutamate SCHEMBL1470464 | 0.80 | GRM8 (0.72) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Glutamic Acid SCHEMBL2593247 | 0.78 | GRM8 (0.69) | GRM8GRM6GRIN2DGRIN3BGSR | |
| D-Glutamate SCHEMBL9474068 | 0.78 | GRM8 (0.69) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL676725 | 0.78 | ALDH1A1 (0.33) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 | |
| SCHEMBL5074626 | 0.78 | CYP1A2 (0.56) | GRM8GRM6GRIN2DGRIN3BGSR | |
| D-Glutamate SCHEMBL1469787 | 0.77 | GRM8 (0.67) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL2538510 | 0.77 | CYP1A2 (0.60) | GRM8GRM6GRIN2DGRIN3BGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117789993-A | Establishment and application of gastric cancer prediction model based on tongue fur metabolite | 浙江省肿瘤医院 | 2024-03-29 | — | — | CN | claimed |
| CN-117789993-B | Establishment and application of gastric cancer prediction model based on tongue fur metabolite | 浙江省肿瘤医院 | 2024-06-11 | — | — | CN | disclosed |
| CN-117789993-A | Establishment and application of gastric cancer prediction model based on tongue fur metabolite | 浙江省肿瘤医院 | 2024-03-29 | — | — | CN | disclosed |
| EP-2888356-A1 | METHODS AND MICROORGANISMS FOR THE BIOLOGICAL SYNTHESIS OF (S)-2-AMINO-6-HYDROXYPIMELATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROATE | Bioamber Inc. (US) | 2015-07-01 | — | — | EP | disclosed |
| US-20150072399-A1 | Methods, Systems And Compositions Related To Reduction Of Conversions Of Microbially Produced 3-Hydroxypropionic Acid (3-HP) To Aldehyde Metabolites | OPX BIOTECHNOLOGIES, INC. (US) | 2015-03-12 | — | — | US | disclosed |
| WO-2014031724-A1 | METHODS AND MICROORGANISMS FOR THE BIOLOGICAL SYNTHESIS OF (S)-2-AMINO-6-HYDROXYPIMELATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROATE | BIOAMBER INC. (US) | 2014-02-27 | — | — | WO | disclosed |
| US-20130189787-A1 | Methods, Systems And Compositions Related To Reduction Of Conversions Of Microbially Produced 3-Hydroxyproplonic Acid (3-HP) To Aldehyde Metabolites | OPX BIOTECHNOLOGIES ,INC. | 2013-07-25 | — | — | US | disclosed |
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |