Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.60 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31006509 | 0.89 | ICMT (0.51) | HSP90AB1P2RX3PSMB1PSMB2PSMB5 | |
| SCHEMBL29283855 | 0.89 | ICMT (0.51) | HSP90AB1P2RX3PSMB1PSMB2PSMB5 | |
| SCHEMBL29283825 | 0.84 | HSP90AB1 (0.65) | HSP90AB1P2RX3GRM2ROCK2ROCK1 | |
| SCHEMBL29283874 | 0.83 | HSP90AB1 (0.64) | HSP90AB1P2RX3GRM2PTPRCPTPN1 | |
| SCHEMBL29283851 | 0.83 | HSP90AB1 (0.64) | HSP90AB1P2RX3GRM2L3MBTL1 | |
| SCHEMBL29283835 | 0.82 | HSP90AB1 (0.63) | HSP90AB1P2RX3GRM2ROCK2ROCK1 | |
| SCHEMBL31006526 | 0.82 | HSP90AB1 (0.63) | HSP90AB1P2RX3GRM2ROCK2ROCK1 | |
| SCHEMBL31006527 | 0.82 | HSP90AB1 (0.76) | HSP90AB1PSMB2GRM2ROCK2ROCK1 | |
| SCHEMBL29283806 | 0.82 | HSP90AB1 (0.76) | HSP90AB1PSMB2GRM2ROCK2ROCK1 | |
| SCHEMBL29283865 | 0.80 | HSP90AB1 (0.69) | HSP90AB1GRM2ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184635-A | Quinolinone compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2024-06-14 | — | — | CN | disclosed |