Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31006557 | 1.00 | HSP90AB1 (0.60) | HSP90AB1ADORA2AGRM2ALDH1A1MAPK1 | |
| SCHEMBL29283807 | 0.89 | ALDH1A1 (0.47) | HSP90AB1ADORA2AALDH1A1MAPK1MEN1 | |
| SCHEMBL31006531 | 0.89 | ALDH1A1 (0.47) | HSP90AB1ADORA2AALDH1A1MAPK1MEN1 | |
| SCHEMBL29283877 | 0.84 | HSP90AB1 (0.65) | HSP90AB1ADORA2AGRM2ALDH1A1MAPK1 | |
| SCHEMBL31006553 | 0.84 | HSP90AB1 (0.65) | HSP90AB1ADORA2AGRM2ALDH1A1MAPK1 | |
| SCHEMBL29283851 | 0.83 | HSP90AB1 (0.64) | HSP90AB1GRM2METAP2 | |
| SCHEMBL29283874 | 0.83 | HSP90AB1 (0.64) | HSP90AB1GRM2FFAR1HDAC6METAP2 | |
| SCHEMBL31006546 | 0.82 | HSP90AB1 (0.63) | HSP90AB1ADORA2AGRM2ALDH1A1MAPK1 | |
| SCHEMBL29283858 | 0.82 | HSP90AB1 (0.63) | HSP90AB1ADORA2AGRM2ALDH1A1MAPK1 | |
| SCHEMBL31006527 | 0.82 | HSP90AB1 (0.76) | HSP90AB1GRM2HDAC6METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184635-A | Quinolinone compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2024-06-14 | — | — | CN | disclosed |