Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2928510 | 1.00 | PTGS1 (0.43) | PTGS1ALDH1A1TDP1ALOX15RECQL | |
| SCHEMBL2931476 | 1.00 | PTGS1 (0.43) | PTGS1ALDH1A1TDP1ALOX15RECQL | |
| SCHEMBL454524 | 0.78 | TSHR (0.44) | PTGS1ALDH1A1TDP1ALOX15RECQL | |
| SCHEMBL454525 | 0.78 | TSHR (0.44) | PTGS1ALDH1A1TDP1ALOX15RECQL | |
| SCHEMBL19379407 | 0.78 | TSHR (0.44) | PTGS1ALDH1A1TDP1ALOX15RECQL | |
| SCHEMBL873402 | 0.75 | — | — | |
| SCHEMBL873403 | 0.75 | — | — | |
| SCHEMBL2931789 | 0.73 | PTGS1 (0.34) | PTGS1ALDH1A1TDP1ALOX15RECQL | |
| SCHEMBL22128166 | 0.73 | ALDH1A1 (0.55) | PTGS1ALDH1A1TDP1ALOX15RECQL | |
| SCHEMBL22128167 | 0.73 | ALDH1A1 (0.55) | PTGS1ALDH1A1TDP1ALOX15RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778645-B2 | Method for the production of glutaconate | BASF SE (DE) | 2014-07-15 | — | — | US | disclosed |
| US-20120021472-A1 | Method for the Production of Glutaconate | BASF SE (DE) | 2012-01-26 | — | — | US | disclosed |
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |
| US-7608450-B2 | Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics | WYETH (US) | 2009-10-27 | — | — | US | disclosed |
| US-7332310-B2 | Mutant of homoserine dehydrogenase from Corynebacterium and DNA encoding thereof | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-02-19 | — | — | US | disclosed |
| US-20060228712-A1 | Incubating the polynucleotide array with at least one of a labeled polynucleotide derived from a coryneform bacterium, a labeled polynucleotide derived from a mutant of the coryneform bacterium or a labeled polynucleotide,detecting any hybridization, analyzing | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-0730027-B1 | Mutant microorganism expressing oxygenase, processes of degrading organic compounds and remediation of the environment, therewith | CANON KK (JP) | 2004-05-06 | — | — | EP | disclosed |
| US-6127144-A | PRODUCING HETEROLOGOUS PROTEINS BY INCUBATING STREPTOMYCES CELL TRANSFORMED WITH NUCLEIC ACID EXPRESSION CONSTRUCT IN PRESENCE OF PEPTIDE-SUSBSTITUTED CHLOROMETHYLKETONE AMINOPEPTIDASE INHIBITOR HAVING DEFINED STRUCTURE | CANGENE CORPORATION (CA) | 2000-10-03 | — | — | US | disclosed |
| US-6004772-A | REMEDYING ENVIRONMENT USING THESE MICROORGANSIMS | CANON KABUSHIKI KAISHA (JP) | 1999-12-21 | — | — | US | disclosed |
| US-5856166-A | ENDOGENOUS TO STREPTOMYCES CELLS DEGRADES HETEROLOGOUS SECRETED FROM STREPTOMYCES HOST CELL | CANGENE CORPORATION (CA) | 1999-01-05 | — | — | US | disclosed |
| US-5616485-A | GENETIC ENGINEERING | CANGENE CORPORATION (CA) | 1997-04-01 | — | — | US | disclosed |
| EP-0731841-A1 | PROTEASES FROM STREPTOMYCES AND USE THEREOF IN PROTEIN EXPRESSION SYSTEMS | Cangene Corporation (CA) | 1996-09-18 | — | — | EP | disclosed |
| EP-0730027-A2 | Mutant microorganismexpressing oxygenase, processes of degrading organic compounds and remediation of the environment, using it | CANON KABUSHIKI KAISHA (JP) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995017512-A2 | PROTEASES FROM STREPTOMYCES AND USE THEREOF IN PROTEIN EXPRESSION SYSTEMS | CANGENE CORPORATION (CA) | 1995-06-29 | — | — | WO | disclosed |
| WO-1992019738-A1 | MICROBIAL DEGRADATION OF TRICHLOROETHYLENE, DICHLOROETHYLENES AND AROMATIC POLLUTANTS | SBP TECHNOLOGIES, INC. (US) | 1992-11-12 | — | — | WO | disclosed |
| US-4859592-A | Production of picolinic acid and pyridine products via pseudomonas | CELGENE CORPORATION | 1989-08-22 | — | — | US | disclosed |
| US-4673646-A | Production of 2-hydroxymuconic semialdehyde | CELANESE CORPORATION (US) | 1987-06-16 | — | — | US | disclosed |
| US-4654303-A | Construction of novel mutant microorganisms | CELANESE CORPORATION (US) | 1987-03-31 | — | — | US | disclosed |
| US-4617156-A | 2-hydroxymuconic semialdehyde bisulfite adduct | CELANESE CORPORATION (US) | 1986-10-14 | — | — | US | disclosed |
| EP-0138391-A1 | Construction of novel mutant micro-organisms | CELGENE CORPORATION (US) | 1985-04-24 | — | — | EP | disclosed |