Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2932663 | 1.00 | PTGS1 (0.34) | PTGS1TSHRALDH1A1ALOX15RECQL | |
| SCHEMBL2928510 | 0.73 | PTGS1 (0.43) | PTGS1TSHRALDH1A1ALOX15RECQL | |
| SCHEMBL2931476 | 0.73 | PTGS1 (0.43) | PTGS1TSHRALDH1A1ALOX15RECQL | |
| SCHEMBL2928506 | 0.73 | PTGS1 (0.43) | PTGS1TSHRALDH1A1ALOX15RECQL | |
| SCHEMBL454525 | 0.72 | TSHR (0.44) | PTGS1TSHRALDH1A1ALOX15RECQL | |
| SCHEMBL19379407 | 0.72 | TSHR (0.44) | PTGS1TSHRALDH1A1ALOX15RECQL | |
| SCHEMBL454524 | 0.72 | TSHR (0.44) | PTGS1TSHRALDH1A1ALOX15RECQL | |
| SCHEMBL10308367 | 0.71 | GABRP (0.35) | ALDH1A1 | |
| SCHEMBL10308366 | 0.71 | GABRP (0.35) | ALDH1A1 | |
| SCHEMBL15563789 | 0.70 | TP53 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408927-B1 | PROBE COMPOUND FOR DETECTING AND ISOLATING ENZYMES AND MEANS AND METHODS USING THE SAME | HELMHOLTZ INFEKTIONSFORSCHUNG (DE) | 2013-11-27 | — | — | EP | disclosed |
| US-20120231972-A1 | Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same | INSTITUTE OF CATALYSIS (CSIC) (ES) | 2012-09-13 | — | — | US | disclosed |
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |
| EP-1737842-B1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INT (DE) | 2010-08-18 | — | — | EP | disclosed |
| US-20090178161-A1 | METHOD FOR DIRECTING NUCLEIC ACIDS TO PLASTIDS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2009-07-09 | — | — | US | disclosed |
| US-5166060-A | Prepared by the action of 2,3-dihydroxybenzoate-3,4-dioxygenase on 2,3-dihydroxybenzoic acid | CELGENE CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120231972-A1 | Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same | SI, GUSB, MPI | PTGS1 3101/4885TSHR 4023/4885ALDH1A1 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.