Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2928510 | 1.00 | PTGS1 (0.43) | PTGS1ALDH1A1TDP1ALOX15RECQL | |
| SCHEMBL2928506 | 1.00 | PTGS1 (0.43) | PTGS1ALDH1A1TDP1ALOX15RECQL | |
| SCHEMBL454524 | 0.78 | TSHR (0.44) | PTGS1ALDH1A1TDP1ALOX15RECQL | |
| SCHEMBL454525 | 0.78 | TSHR (0.44) | PTGS1ALDH1A1TDP1ALOX15RECQL | |
| SCHEMBL19379407 | 0.78 | TSHR (0.44) | PTGS1ALDH1A1TDP1ALOX15RECQL | |
| SCHEMBL873402 | 0.75 | — | — | |
| SCHEMBL873403 | 0.75 | — | — | |
| SCHEMBL2931789 | 0.73 | PTGS1 (0.34) | PTGS1ALDH1A1TDP1ALOX15RECQL | |
| SCHEMBL22128166 | 0.73 | ALDH1A1 (0.55) | PTGS1ALDH1A1TDP1ALOX15RECQL | |
| SCHEMBL22128167 | 0.73 | ALDH1A1 (0.55) | PTGS1ALDH1A1TDP1ALOX15RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |