Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31439858 | 0.79 | CTSA (0.47) | FFAR1PKM | |
| SCHEMBL31038549 | 0.79 | PDE5A (0.43) | FFAR1TRPV3LTA4HPTGESALOX5 | |
| SCHEMBL2524154 | 0.78 | L3MBTL1 (0.52) | SMN1; SMN2TRPV3PKMALOX5GRM5 | |
| SCHEMBL20085570 | 0.77 | TRPV3 (0.51) | TRPV3PKMALOX5 | |
| SCHEMBL23834867 | 0.77 | LMNA (0.49) | FFAR1KMT2ASMN1; SMN2TRPV3PKM | |
| SCHEMBL29920882 | 0.77 | LMNA (0.49) | FFAR1KMT2ASMN1; SMN2TRPV3PKM | |
| SCHEMBL3924169 | 0.77 | TRPV3 (0.45) | FFAR1KMT2ASMN1; SMN2TRPV3GRM5 | |
| SCHEMBL28408442 | 0.75 | TRPV3 (0.49) | TRPV3LTA4HPKMGRM5 | |
| SCHEMBL8623878 | 0.74 | PTGER1 (0.62) | KMT2ATRPV3ALKBH1PTGER1NR4A2 | |
| SCHEMBL25226481 | 0.72 | TRPV3 (0.44) | FFAR1TRPV3LTA4HFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271299-A | Lactam compound, and preparation method and application thereof | 广州市联瑞制药有限公司 | 2024-07-02 | — | — | CN | disclosed |