SCHEMBL29285291

SCHEMBL29285291

CC(C(=O)O)c1c(N)cccc1C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 11/20 0.45
AKR1C2 P52895 11/20 0.45
AKR1C4 P17516 1/20 0.40
AKR1C1 Q04828 1/20 0.40
CTSS P25774 2/20 0.37
CTSK P43235 1/20 0.37
POLQ O75417 1/20 0.36
KCNH2 Q12809 2/20 0.36
ESR1 P03372 1/20 0.36
RBP4 P02753 2/20 0.36
ADRA2C P18825 1/20 0.36
MAOA P21397 1/20 0.36
ADRA1A P35348 1/20 0.36
DRD3 P35462 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30428096 0.88 AKR1C3 (0.50) AKR1C3AKR1C2AKR1C4AKR1C1CTSS
SCHEMBL1000720 0.82 PTGS2 (0.44) AKR1C3AKR1C2KCNH2ESR1ADRA2C
SCHEMBL10701887 0.80 P2RX7 (0.39) CTSSCTSKKCNH2ESR1ADRA1A
SCHEMBL29010004 0.79 AKR1C3 (0.44) AKR1C3AKR1C2AKR1C4AKR1C1CTSS
SCHEMBL25413584 0.79 P2RX7 (0.41) CTSSCTSKKCNH2ESR1CYP3A4
SCHEMBL10588711 0.76 CD44 (0.42) AKR1C3AKR1C2KCNH2ADRA2CMAOA
SCHEMBL24450634 0.73 AR (0.39) CTSSCTSKKCNH2ESR1HPGD
SCHEMBL194437 0.73 AKR1C3 (0.52) AKR1C3AKR1C2POLQ
SCHEMBL30428161 0.73 AKR1C3 (0.52) AKR1C3AKR1C2POLQ
SCHEMBL6675162 0.72 LMNA (0.43) AKR1C3AKR1C2POLQHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146146-B Hapten for detecting flunixin meglumine content and application thereof 北京勤邦科技股份有限公司 2024-07-05 CN claimed
CN-118146146-A Hapten for detecting flunixin meglumine content and application thereof 北京勤邦科技股份有限公司 2024-06-07 CN claimed
CN-118146146-B Hapten for detecting flunixin meglumine content and application thereof 北京勤邦科技股份有限公司 2024-07-05 CN disclosed
CN-118146146-A Hapten for detecting flunixin meglumine content and application thereof 北京勤邦科技股份有限公司 2024-06-07 CN disclosed