Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 7/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | UGCG | Q16739 | 1/20 | 0.45 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4483666 | 0.96 | L3MBTL1 (0.59) | L3MBTL1TDP1APPCA1CA2 | |
| SCHEMBL9234752 | 0.91 | L3MBTL1 (0.62) | L3MBTL1TDP1APPCA1CA2 | |
| SCHEMBL16614410 | 0.90 | L3MBTL1 (0.65) | L3MBTL1TDP1APPCA1CA2 | |
| SCHEMBL6551488 | 0.90 | L3MBTL1 (0.65) | L3MBTL1TDP1APPCA1CA2 | |
| SCHEMBL27089915 | 0.90 | L3MBTL1 (0.65) | L3MBTL1TDP1APPCA1CA2 | |
| SCHEMBL1009895 | 0.90 | L3MBTL1 (0.65) | L3MBTL1TDP1APPCA1CA2 | |
| SCHEMBL16093231 | 0.89 | APP (0.57) | L3MBTL1TDP1APPCA1CA2 | |
| SCHEMBL15532554 | 0.89 | APP (0.57) | L3MBTL1TDP1APPCA1CA2 | |
| SCHEMBL4741980 | 0.85 | TDP1 (0.54) | L3MBTL1TDP1APPCA1CA2 | |
| SCHEMBL8499580 | 0.85 | IDO1 (0.61) | L3MBTL1TDP1APPCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317784-A | Pyrrolo-benzodiazepine derivative and conjugate thereof, and preparation method and application thereof | 江苏恒瑞医药股份有限公司 | 2024-07-09 | — | — | CN | disclosed |