SCHEMBL4741980

SCHEMBL4741980

COc1ccc(COCCO)cc1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
IDO1 P14902 3/20 0.53
AGXT P21549 2/20 0.53
APP P05067 7/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CALM1 P0DP23 1/20 0.48
HTT P42858 1/20 0.47
NPC1 O15118 1/20 0.46
POLB P06746 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CHRM3 P20309 2/20 0.46
MAOB P27338 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15532554 0.96 APP (0.57) TDP1L3MBTL1IDO1AGXTAPP
SCHEMBL16093231 0.96 APP (0.57) TDP1L3MBTL1IDO1AGXTAPP
SCHEMBL4483666 0.89 L3MBTL1 (0.59) TDP1L3MBTL1IDO1AGXTAPP
SCHEMBL8499580 0.87 IDO1 (0.61) TDP1L3MBTL1IDO1AGXTAPP
SCHEMBL9234752 0.87 L3MBTL1 (0.62) TDP1L3MBTL1IDO1AGXTAPP
SCHEMBL6551488 0.85 L3MBTL1 (0.65) TDP1L3MBTL1IDO1AGXTAPP
SCHEMBL16614410 0.85 L3MBTL1 (0.65) TDP1L3MBTL1IDO1AGXTAPP
SCHEMBL29285378 0.85 L3MBTL1 (0.56) TDP1L3MBTL1IDO1AGXTAPP
SCHEMBL27089915 0.85 L3MBTL1 (0.65) TDP1L3MBTL1IDO1AGXTAPP
SCHEMBL1009895 0.85 L3MBTL1 (0.65) TDP1L3MBTL1IDO1AGXTAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647434-A1 MODULATOR FOR PROMOTING BINDING OF BUTYROPHILIN 3A1/2A1 Unicet Biotech Co., LLC (CN) 2025-11-12 EP disclosed
US-20240360163-A1 Nucleoside Prodrugs and Uses Related Thereto UNIV EMORY (US) 2024-10-31 US disclosed
US-12049474-B2 Nucleoside prodrugs and uses related thereto EMORY UNIVERSITY (US) 2024-07-30 US disclosed
WO-2024146627-A1 MODULATOR FOR PROMOTING BINDING OF BUTYROPHILIN 3A1/2A1 北京清辉联诺生物科技有限责任公司 2024-07-11 WO disclosed
CN-118317784-A Pyrrolo-benzodiazepine derivative and conjugate thereof, and preparation method and application thereof 江苏恒瑞医药股份有限公司 2024-07-09 CN disclosed
US-20240165259-A1 BIOORTHOGONAL REACTION SUITABLE FOR CLICK/UNCLICK APPLICATIONS DANA-FARBER CANCER INSTITUTE, INC. (US) 2024-05-23 US disclosed
EP-4320073-A1 BIOORTHOGONAL REACTION SUITABLE FOR CLICK/UNCLICK APPLICATIONS Dana-Farber Cancer Institute, Inc. (US) 2024-02-14 EP disclosed
US-20240043467-A1 5'-SUBSTITUTED NUCLEOSIDE MONOPHOSPHATES, PRODRUGS THEREOF, AND USES RELATED THERETO EMORY UNIVERSITY (US) 2024-02-08 US disclosed
CN-117337267-A Bioorthogonal reactions suitable for click/click cancellation applications 达纳-法伯癌症研究所公司 2024-01-02 CN disclosed
EP-4204428-A1 5'-SUBSTITUTED NUCLEOSIDE MONOPHOSPHATES, PRODRUGS THEREOF, AND USES RELATED THERETO Emory University (US) 2023-07-05 EP disclosed
US-4584396-A Substituted phenoxypropionates and herbicidal compositions NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-04-22 US disclosed
EP-0068260-B1 SUBSTITUTED PHENOXYPROPIONATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-03-05 EP disclosed
EP-0086392-B1 HERBICIDAL AGENT CONTAINING METAMITRON IN COMBINATION WITH CERTAIN PHENOXYPROPIONIC-ACID ESTERS BAYER AG (DE) 1985-08-21 EP disclosed
US-4441913-A PRE- AND POST-EMERGENCE NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1984-04-10 US disclosed
EP-0086392-A1 Herbicidal agent containing metamitron in combination with certain phenoxypropionic-acid esters BAYER AG (DE) 1983-08-24 EP disclosed
EP-0084819-A2 Herbicidal agents containing methabenzthiazuron in combination with certain phenoxypropionic acid esters BAYER AG (DE) 1983-08-03 EP disclosed
EP-0068260-A2 Substituted phenoxypropionates, process for their preparation and their use as herbicides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1983-01-05 EP disclosed
US-4008226-A ANTIBIOTIC AMERICAN HOME PRODUCTS CORPORATION (US) 1977-02-15 US disclosed
US-3993768-A FUNGICIDES SYNTEX (U.S.A.) INC. (US) 1976-11-23 US disclosed
US-3962215-A PHOSPHORYLATION, ACYLATION, WATER, ACID CHLORIDE, ALCOHOL AMERICAN HOME PRODUCTS CORPORATION (US) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360163-A1 Nucleoside Prodrugs and Uses Related Thereto PNPO, GSTO1, CYP2C18 TDP1 1205/4885L3MBTL1 4216/4885IDO1 1110/4885
US-12049474-B2 Nucleoside prodrugs and uses related thereto PNPO, GSTO1, CYP2C18 TDP1 1205/4885L3MBTL1 4216/4885IDO1 1110/4885
US-20240165259-A1 BIOORTHOGONAL REACTION SUITABLE FOR CLICK/UNCLICK APPLICATIONS CILK1, SYMPK, DCK TDP1 3667/4885L3MBTL1 3251/4885IDO1 2753/4885
US-20240043467-A1 5'-SUBSTITUTED NUCLEOSIDE MONOPHOSPHATES, PRODRUGS THEREOF, AND USES RELATED THERETO PNP, ENTPD5, TYMP TDP1 216/4885L3MBTL1 2121/4885IDO1 1733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.