Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491576 | 0.86 | KDM4E (0.64) | LTA4HKDM4EALDH1A1TDP1POLB | |
| SCHEMBL14591679 | 0.85 | KDM4E (0.62) | LTA4HKDM4EALDH1A1TDP1POLB | |
| SCHEMBL5284881 | 0.85 | KDM4E (0.62) | LTA4HKDM4EALDH1A1TDP1POLB | |
| SCHEMBL491707 | 0.85 | KDM4E (0.62) | LTA4HKDM4EALDH1A1TDP1POLB | |
| Oxalic Acid SCHEMBL5856288 | 0.79 | KDM4E (0.77) | KDM4EALDH1A1TDP1POLBLMNA | |
| Oxalic Acid SCHEMBL5856307 | 0.78 | KDM4E (0.75) | KDM4EALDH1A1TDP1POLBLMNA | |
| SCHEMBL6052619 | 0.77 | HRH3 (0.65) | LTA4HKDM4EALDH1A1 | |
| SCHEMBL5281831 | 0.76 | HRH3 (0.64) | LTA4HKDM4EALDH1A1 | |
| SCHEMBL19273423 | 0.74 | LTA4H (0.75) | LTA4HKDM4EALDH1A1GRIN2AGRIN2B | |
| SCHEMBL7427501 | 0.74 | ALDH1A1 (0.61) | LTA4HKDM4EALDH1A1POLBGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324715-A | Compounds, compositions, and methods of use thereof | 艾勒维生技公司 | 2024-07-12 | — | — | CN | disclosed |