Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181061 | 0.85 | ALDH1A1 (0.41) | S1PR2MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6036823 | 0.84 | S1PR2 (0.43) | S1PR2BCHEACHEMAPTALDH1A1 | |
| SCHEMBL9426950 | 0.82 | MEN1 (0.48) | S1PR2BCHEACHEMAPTALDH1A1 | |
| SCHEMBL998315 | 0.82 | KMT2A (0.39) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6982295 | 0.79 | S1PR2 (0.44) | S1PR2BCHEACHEMAPTALDH1A1 | |
| SCHEMBL9650144 | 0.77 | RECQL (0.41) | ALDH1A1FFAR1NFE2L2HTT | |
| SCHEMBL3654232 | 0.76 | S1PR2 (0.41) | S1PR2BCHEACHEMAPTALDH1A1 | |
| SCHEMBL9426497 | 0.76 | S1PR2 (0.41) | S1PR2BCHEACHEKDM4ESMN1; SMN2 | |
| SCHEMBL1368673 | 0.74 | S1PR2 (0.40) | S1PR2BCHEACHEMAPTALDH1A1 | |
| SCHEMBL9649784 | 0.74 | CA2 (0.43) | S1PR2BCHEACHEMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225223-B1 | ORGANIC COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2017-01-11 | — | — | EP | disclosed |
| EP-2205590-B1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2014-06-04 | — | — | EP | disclosed |
| EP-2251338-A2 | Organic compounds | Boehringer Ingelheim International GmbH (DE) | 2010-11-17 | — | — | EP | disclosed |
| EP-2225223-A2 | ORGANIC COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2010-09-08 | — | — | EP | disclosed |
| EP-2205590-A1 | CGRP ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009065919-A2 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009050232-A1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |
| WO-2002050072-A1 | DICHLOROPYRIDINE CARBAMIDES | BAYER CROPSCIENCE AG (DE) | 2002-06-27 | — | — | WO | disclosed |
| EP-0244728-B1 | USE OF HETEROARYLETHYL AMINES TO STIMULATE ANIMAL GROWTH, HETEROARYLETHYL AMINES AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0450180-A2 | Process for the preparation of aminoethanol derivatives | BAYER AG (DE) | 1991-10-09 | — | — | EP | disclosed |
| EP-0368176-A1 | Esters of carboximidic acid, their preparation, and their use as pesticides | CIBA-GEIGY AG (CH) | 1990-05-16 | — | — | EP | disclosed |
| EP-0244728-A2 | Use of heteroarylethyl amines to stimulate animal growth, heteroarylethyl amines and process for their preparation | BAYER AG (DE) | 1987-11-11 | — | — | EP | disclosed |
| EP-0013361-B1 | SUBSTITUTED N-HALOGENOMETHYL ANILIDES, PROCESS FOR THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1981-09-16 | — | — | EP | disclosed |
| EP-0013361-A2 | Substituted N-halogenomethyl anilides, process for their preparation and use | BASF Aktiengesellschaft (DE) | 1980-07-23 | — | — | EP | disclosed |
| EP-0013360-A2 | N-substituted carboxylic acid anilides, process for their preparation as well as their use as fungicides | BASF Aktiengesellschaft (DE) | 1980-07-23 | — | — | EP | disclosed |