Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 3/20 | 0.52 |
| ▸ | MMP1 | P03956 | 2/20 | 0.52 |
| ▸ | MMP13 | P45452 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2927569 | 0.88 | MMP9 (0.50) | MMP9MMP1MMP13USP2MEN1 | |
| SCHEMBL2929201 | 0.88 | MMP9 (0.46) | MMP9MMP1MMP13USP2MMP3 | |
| SCHEMBL2928574 | 0.84 | MMP9 (0.49) | MMP9MMP1MMP13KMT2AMMP3 | |
| SCHEMBL2930771 | 0.80 | ALDH1A1 (0.43) | CYP3A4USP2CYP2D6CYP1A2SMN1; SMN2 | |
| SCHEMBL2927062 | 0.77 | MMP9 (0.51) | MMP9MMP1MMP13MEN1KMT2A | |
| SCHEMBL1658424 | 0.76 | MMP9 (0.62) | MMP9MMP1MMP13CYP3A4USP2 | |
| SCHEMBL1655572 | 0.76 | MMP9 (0.59) | MMP9MMP1MMP13CYP3A4USP2 | |
| SCHEMBL2927853 | 0.75 | MMP9 (0.47) | MMP9MMP1MMP13HCRTR1HCRTR2 | |
| SCHEMBL2927673 | 0.75 | MMP9 (0.54) | MMP9MMP1MMP13CYP3A4USP2 | |
| SCHEMBL1658411 | 0.75 | MMP9 (0.45) | MMP9MMP1MMP13MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768979-B1 | OCTAHYDROPYRROLO[2, 3, C]PYRIDINE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | MERCK SERONO SA (CH) | 2010-09-29 | — | — | EP | claimed |