Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 14/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 14/20 | 0.46 |
| ▸ | MMP3 | P08254 | 8/20 | 0.46 |
| ▸ | MMP7 | P09237 | 7/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 11/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2927853 | 0.90 | MMP9 (0.47) | MMP9MMP2MMP12MMP1MMP3 | |
| SCHEMBL1658411 | 0.87 | MMP9 (0.45) | MMP9MMP2MMP12MMP1MMP3 | |
| SCHEMBL2928560 | 0.77 | MMP9 (0.52) | MMP9MMP2MMP12MMP1MMP3 | |
| SCHEMBL2927569 | 0.77 | MMP9 (0.50) | MMP9MMP2MMP12MMP1MMP3 | |
| SCHEMBL2929201 | 0.76 | MMP9 (0.46) | MMP9MMP2MMP12MMP1MMP3 | |
| SCHEMBL2928574 | 0.73 | MMP9 (0.49) | MMP9MMP2MMP12MMP1MMP3 | |
| SCHEMBL2927547 | 0.70 | MMP9 (0.75) | MMP9MMP2MMP12MMP1MMP3 | |
| SCHEMBL2927653 | 0.70 | MMP9 (0.68) | MMP9MMP2MMP12MMP1MMP3 | |
| SCHEMBL2930771 | 0.69 | ALDH1A1 (0.43) | PKM | |
| SCHEMBL5546935 | 0.68 | MMP9 (0.61) | MMP9MMP2MMP12MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768979-B1 | OCTAHYDROPYRROLO[2, 3, C]PYRIDINE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | MERCK SERONO SA (CH) | 2010-09-29 | — | — | EP | claimed |