Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.48 |
| ▸ | STS | P08842 | 4/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12547054 | 0.85 | HPGDS (0.48) | HPGDSGPR119 | |
| SCHEMBL12547063 | 0.85 | GPR119 (0.53) | HPGDSGPR119KDM4EPKM | |
| SCHEMBL22310758 | 0.83 | GPR119 (0.45) | HPGDSGPR119 | |
| SCHEMBL1951257 | 0.83 | GPR119 (0.52) | HPGDSGPR119KMT2A | |
| SCHEMBL1321592 | 0.82 | MET (0.52) | HPGDSGPR119 | |
| SCHEMBL31690168 | 0.79 | EPHX2 (0.47) | HPGDSGPR119 | |
| Tert-Butyl Formate SCHEMBL29286245 | 0.78 | PIK3CA (0.39) | HPGDSKMT2A | |
| SCHEMBL19266990 | 0.78 | PDE4D (0.48) | HPGDSGPR119USP30 | |
| SCHEMBL22310368 | 0.77 | HPGDS (0.47) | HPGDSGPR119 | |
| SCHEMBL12547453 | 0.77 | CHEK2 (0.47) | HPGDSGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359587-A | Synthesis method of 4- (((2- (3- (hydroxymethyl) phenyl) pyrimidine-5-yl) oxo) methyl) piperidine-1-tert-butyl formate | 上海法默生物科技有限公司 | 2024-07-19 | — | — | CN | disclosed |