Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3642592 | 0.87 | ALOX15 (0.58) | TSHRALDH1A1ALOX15HPGDSMN1; SMN2 | |
| SCHEMBL8491404 | 0.82 | TSHR (0.55) | TSHRALDH1A1ALOX15KMT2APOLB | |
| SCHEMBL13911244 | 0.81 | CXCR2 (0.49) | TSHRALDH1A1CXCR2KMT2APOLB | |
| SCHEMBL3530832 | 0.80 | TSHR (0.57) | TSHRALDH1A1ALOX15KMT2APOLB | |
| SCHEMBL28175221 | 0.79 | ALOX15 (0.50) | TSHRALDH1A1ALOX15HPGDSMN1; SMN2 | |
| SCHEMBL27745300 | 0.74 | CXCR2 (0.44) | TSHRALDH1A1ALOX15CXCR2KMT2A | |
| SCHEMBL9657607 | 0.73 | ALDH1A1 (0.43) | TSHRALDH1A1ALOX15CXCR2KMT2A | |
| SCHEMBL27993341 | 0.73 | ALDH1A1 (0.45) | TSHRALDH1A1ALOX15CXCR2KMT2A | |
| SCHEMBL9317962 | 0.73 | TSHR (0.57) | TSHRALDH1A1ALOX15KMT2ALMNA | |
| SCHEMBL11373594 | 0.71 | ALOX15 (0.57) | TSHRALDH1A1ALOX15LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071493-A | Pesticidally active heterocyclic derivatives with sulphur containing substituents | 先正达参股股份有限公司 | 2018-12-21 | — | — | CN | disclosed |