Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11373594 | 0.88 | ALOX15 (0.57) | TSHRALDH1A1ALOX15LMNAMAPT | |
| SCHEMBL27294789 | 0.85 | ALDH1A1 (0.47) | TSHRALDH1A1ALOX15KMT2APOLB | |
| SCHEMBL2793862 | 0.83 | ATM (0.44) | TSHRALDH1A1ALOX15KMT2APOLB | |
| SCHEMBL8491404 | 0.83 | TSHR (0.55) | TSHRALDH1A1ALOX15PBRM1KMT2A | |
| SCHEMBL20501208 | 0.80 | TSHR (0.39) | TSHRALDH1A1KMT2APOLBMAPT | |
| SCHEMBL29286648 | 0.80 | TSHR (0.52) | TSHRALDH1A1ALOX15PBRM1KMT2A | |
| SCHEMBL1500751 | 0.79 | ALDH1A1 (0.53) | TSHRALDH1A1ALOX15KMT2APOLB | |
| SCHEMBL5188312 | 0.79 | ALB (0.53) | TSHRALDH1A1ALOX15HPGDTTR | |
| SCHEMBL7033458 | 0.79 | NR4A2 (0.48) | TSHRALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL181454 | 0.79 | ALDH1A1 (0.46) | TSHRALDH1A1KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850125-B | Method for preparing benzenesulfonyl chloride compound by continuous flow | 爱斯特（成都）生物制药股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-115850125-A | Method for preparing benzene sulfonyl chloride compound by continuous flow | 爱斯特（成都）生物制药股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-106535901-A | A new class of mu-opioid receptor agonists | 哥伦比亚大学董事会 | 2017-03-22 | — | — | CN | disclosed |
| US-7645771-B2 | CCR5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORP. (US) | 2010-01-12 | — | — | US | disclosed |
| US-20060229336-A1 | Ccr5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORPORATION | 2006-10-12 | — | — | US | disclosed |
| CN-1744899-A | Piperidine derivatives as CCR5 antagonists | SMITHKLINE BEECHAM CORP (US) | 2006-03-08 | — | — | CN | disclosed |
| EP-1569646-A2 | PIPERIDINE DERIVATIVES AS CCR5 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004054974-A2 | PIPERIDINE DERIVATIVES AS CCR5 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-07-01 | — | — | WO | disclosed |
| US-4060549-A | Process for preparing sulfonic acid fluorides | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229336-A1 | Ccr5 antagonists as therapeutic agents | CCR5, CCR1, CXCR3 | TSHR 2546/4885ALDH1A1 2787/4885ALOX15 1639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.