Acrylic Acid

Acrylic Acid

SCHEMBL29286992

C=C(C)C(=O)OC.C=CC(=O)O.C=CCOC(=O)C(=C)C

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
TSHR P16473 5/20 0.43
THRB P10828 1/20 0.37
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
LMNA P02545 2/20 0.34
MAPT P10636 3/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2358955 0.93 ALDH1A1 (0.60) ALDH1A1TSHRTHRBHSD17B10LMNA
Acrylic Acid SCHEMBL278318 0.93 TSHR (0.44) ALDH1A1TSHRTHRBALOX15HSD17B10
Acrylic Acid SCHEMBL6390284 0.93 TSHR (0.44) ALDH1A1TSHRTHRBALOX15HSD17B10
Acrylic Acid SCHEMBL458980 0.91 TSHR (0.42) ALDH1A1TSHRTHRBALOX15HSD17B10
SCHEMBL28843514 0.88 ALDH1A1 (0.48) ALDH1A1TSHRTHRBLMNAMAPT
Acrylic Acid SCHEMBL1173079 0.86 TSHR (0.39) ALDH1A1TSHRTHRBALOX15HSD17B10
Acrylic Acid SCHEMBL1173491 0.86 TDP1 (0.41) ALDH1A1TSHRTHRBALOX15HSD17B10
Acetic Acid SCHEMBL8775549 0.85 TSHR (0.47) ALDH1A1TSHRTHRBHSD17B10LMNA
Bicarbonate SCHEMBL2301694 0.85 TSHR (0.47) ALDH1A1TSHRTHRBHSD17B10LMNA
Bicarbonate SCHEMBL28114546 0.85 TSHR (0.47) ALDH1A1TSHRTHRBHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109153838-A Polymer composition containing poly- (methyl methacrylate) and impact modifier composition SABIC环球技术有限责任公司 2019-01-04 CN disclosed