Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.77 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057451 | 0.97 | HRH3 (0.82) | HRH3 | |
| SCHEMBL31484892 | 0.85 | HRH3 (0.78) | HRH3NPC1TP53RAB9A | |
| SCHEMBL3031580 | 0.85 | HRH3 (0.78) | HRH3 | |
| SCHEMBL3041814 | 0.85 | HRH3 (0.57) | HRH3 | |
| SCHEMBL1241202 | 0.84 | ALDH1A1 (0.68) | HRH3 | |
| SCHEMBL7811609 | 0.84 | NPC1 (0.78) | HRH3NPC1TP53RAB9A | |
| SCHEMBL3034002 | 0.84 | HRH3 (0.61) | HRH3NPC1TP53RAB9A | |
| SCHEMBL7139221 | 0.81 | LTA4H (0.75) | HRH3 | |
| SCHEMBL21348251 | 0.81 | HRH3 (0.66) | HRH3NPC1TP53RAB9A | |
| SCHEMBL1239274 | 0.80 | HRH3 (0.74) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108912029-A | Nitrogen-containing heterocycle amide derivatives and application thereof | 广东东阳光药业有限公司 | 2018-11-30 | — | — | CN | disclosed |
| US-20100216762-A1 | Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof | ABBOTT LABORATORIES (US) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216762-A1 | Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof | S1PR5, LPAR5, S1PR1 | HRH3 469/4885NPC1 965/4885TP53 4509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.