SCHEMBL29288485

SCHEMBL29288485

CC(=O)N1CC=Cc2ccccc21.c1c[nH]nn1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 5/20 0.39
NOTUM Q6P988 9/20 0.38
P2RX4 Q99571 4/20 0.35
P2RX1 P51575 2/20 0.34
P2RX3 P56373 2/20 0.34
P2RX7 Q99572 2/20 0.34
PTBP1 P26599 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
AMPD2 Q01433 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1477941 0.84 NOTUM (0.46) HSD17B3NOTUMP2RX4P2RX1P2RX3
SCHEMBL28466524 0.78 HSD17B3 (0.39) HSD17B3NOTUM
SCHEMBL27785934 0.71 P2RX4 (0.58) P2RX4P2RX1P2RX3P2RX7SMN1; SMN2
SCHEMBL3375661 0.70 P2RX4 (0.44) HSD17B3P2RX4P2RX1P2RX3P2RX7
SCHEMBL29376182 0.70 P2RX4 (0.44) HSD17B3P2RX4P2RX1P2RX3P2RX7
SCHEMBL5042828 0.69 HSD17B3 (0.47) HSD17B3NOTUMP2RX4P2RX1P2RX3
SCHEMBL5042834 0.69 HSD17B3 (0.47) HSD17B3NOTUMP2RX4P2RX1P2RX3
SCHEMBL205655 0.69 SMN1; SMN2 (0.53) NOTUMP2RX4P2RX1P2RX3P2RX7
SCHEMBL29549990 0.69 SMN1; SMN2 (0.53) NOTUMP2RX4P2RX1P2RX3P2RX7
SCHEMBL1286806 0.69 LMNA (0.55) HSD17B3P2RX4P2RX1P2RX3P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109400588-A One kind quinoxaline containing flutrimazole fungicide, preparation method and applications 湖北文理学院 2019-03-01 CN disclosed