Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 15/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 6/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376182 | 1.00 | P2RX4 (0.44) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL3241414 | 0.86 | P2RX4 (0.42) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL8705933 | 0.84 | P2RX4 (0.57) | P2RX4LMNATSHRMAPK1SCN4A | |
| Indole SCHEMBL28214491 | 0.84 | TRPA1 (0.45) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL1477941 | 0.84 | NOTUM (0.46) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL1286806 | 0.84 | LMNA (0.55) | P2RX4LMNATSHRMAPK1SCN4A | |
| Quinoline SCHEMBL28157604 | 0.83 | ALDH1A1 (0.44) | P2RX4LMNAMAPK1MEN1KMT2A | |
| Isoquinoline SCHEMBL28075529 | 0.83 | P2RX4 (0.38) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL7832555 | 0.82 | P2RX4 (0.42) | P2RX4LMNATSHRMAPK1SCN4A | |
| Hydrochloric Acid SCHEMBL28145471 | 0.82 | LMNA (0.53) | P2RX4LMNATSHRMAPK1SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029076-B | Benzo piperazine composition as BET bromine domain inhibitor | 福马疗法公司 | 2019-06-07 | — | — | CN | claimed |
| CN-109843298-A | The combination treatment of utilization method Buddhist nun ester X receptor (FXR) regulator | 阿卡纳治疗学有限公司 | 2019-06-04 | — | — | CN | claimed |
| CN-104910148-B | Aminotriazole(ATA) and pyridine and its as kinase inhibitor purposes | 西格诺药品有限公司 | 2017-06-27 | — | — | CN | claimed |
| EP-2970129-A2 | CRYSTALS OF LAQUINIMOD SODIUM AND IMPROVED PROCESS FOR THE MANUFACTURE THEREOF | Teva Pharmaceutical Industries Ltd. (IL) | 2016-01-20 | — | — | EP | claimed |
| WO-2014153145-A2 | CRYSTALS OF LAQUINIMOD SODIUM AND IMPROVED PROCESS FOR THE MANUFACTURE THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2014-09-25 | — | — | WO | claimed |
| EP-0934276-B1 | ANTHRANILIC ACID DERIVATIVES AS MULTI DRUG RESISTANCE MODULATORS | XENOVA LTD (GB) | 2003-12-17 | — | — | EP | claimed |
| CN-1458840-A | Pharmaceutical composition of cholesteryl ester transfer protein inhibitor | PFIZER PROD INC (US) | 2003-11-26 | — | — | CN | claimed |
| EP-0885232-A1 | NOVEL 1(2H) QUINOLINE CARBOXYLIC ACID DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR SYNTHESISING SUBSTANCES HAVING ANTIBIOTIC PROPERTIES | HOECHST MARION ROUSSEL (FR) | 1998-12-23 | — | — | EP | claimed |
| WO-1997031926-A1 | NOVEL 1(2H) QUINOLINE CARBOXYLIC ACID DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR SYNTHESISING SUBSTANCES HAVING ANTIBIOTIC PROPERTIES | HOECHST MARION ROUSSEL (FR) | 1997-09-04 | — | — | WO | claimed |
| US-4013468-A | Method of hardening a protein-containing layer of a silver halide photographic material with an alkyl ester of 1,2-dihydroquinoline-N-carboxylic acid | AGFA-GEVAERT, A.G. (DT) | 1977-03-22 | — | — | US | claimed |
| CN-119954828-A | Parallel ring compound and preparation and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-116322699-B | Parallel ring compound and preparation and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2025-02-11 | — | — | CN | disclosed |
| EP-4392425-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS AS PARP INHIBITORS AND USE THEREOF | Impact Therapeutics (Shanghai), Inc. (CN) | 2024-07-03 | — | — | EP | disclosed |
| WO-2024109671-A1 | CAS9 PROTEIN, VARIANTS, OR HOMOLOGUES THEREOF-SPECIFIC PROTAC DEGRADERS AND USES THEREOF | GLUETACS THERAPEUTICS (SHANGHAI) CO., LTD. (CN) | 2024-05-30 | — | — | WO | disclosed |
| WO-2023241627-A1 | CDK8/19 DUAL INHIBITORS AND METHODS OF USE THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-12-21 | — | — | WO | disclosed |
| WO-1998032442-A1 | QUINOXALINE IN TRIPLE COMBINATION WITH PROTEASE INHIBITORS AND REVERSE TRANSCRIPTASE INHIBITORS AS MEDICINES FOR TREATING AIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-30 | — | — | WO | disclosed |
| WO-1997031926-A1 | NOVEL 1(2H) QUINOLINE CARBOXYLIC ACID DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR SYNTHESISING SUBSTANCES HAVING ANTIBIOTIC PROPERTIES | HOECHST MARION ROUSSEL (FR) | 1997-09-04 | — | — | WO | disclosed |
| WO-1993012091-A1 | D- AND L-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-1-CARBOXYLIC ACIDS AND THEIR DERIVATIVES CONTAINING URETHANE-TYPE N-PROTECTING GROUPS AS WELL AS A PROCESS FOR PREPARING THEM AND THE CORRESPONDING RACEMATES | Gyógyszerkutató Intézet Kft. (HU) | 1993-06-24 | — | — | WO | disclosed |
| US-4013468-A | Method of hardening a protein-containing layer of a silver halide photographic material with an alkyl ester of 1,2-dihydroquinoline-N-carboxylic acid | AGFA-GEVAERT, A.G. (DT) | 1977-03-22 | — | — | US | disclosed |
| US-4013468-A | Method of hardening a protein-containing layer of a silver halide photographic material with an alkyl ester of 1,2-dihydroquinoline-N-carboxylic acid | AGFA-GEVAERT, A.G. (DT) | 1977-03-22 | — | — | US | disclosed |