Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | CTSA | P10619 | 6/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29288506 | 1.00 | FFAR1 (0.46) | FFAR1CTSAPRNPNPSR1RXFP1 | |
| SCHEMBL16679989 | 0.98 | FFAR1 (0.47) | FFAR1CTSAPRNPNPSR1RXFP1 | |
| SCHEMBL16679992 | 0.98 | FFAR1 (0.47) | FFAR1CTSAPRNPNPSR1RXFP1 | |
| SCHEMBL1138669 | 0.83 | CYP26A1 (0.51) | FFAR1CTSAALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1138687 | 0.83 | ALDH1A1 (0.52) | CTSAEEF2KALDH1A1SMN1; SMN2HPGD | |
| Lithium Ion SCHEMBL29562413 | 0.83 | FAAH (0.39) | ALDH1A1SLC6A9HPGDLMNAGAA | |
| SCHEMBL20993600 | 0.83 | HTT (0.54) | NPSR1ALDH1A1HPGDLMNAGAA | |
| SCHEMBL28008554 | 0.83 | HTT (0.54) | NPSR1ALDH1A1HPGDLMNAGAA | |
| SCHEMBL23722450 | 0.82 | EEF2K (0.47) | FFAR1CTSAPRNPNPSR1RXFP1 | |
| Hydrochloric Acid SCHEMBL350883 | 0.81 | ALDH1A1 (0.51) | CTSAEEF2KALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109414441-A | Quinazoline and indole compounds for the treatment of medical disorders | 艾其林医药公司 | 2019-03-01 | — | — | CN | disclosed |