Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 10/20 | 0.40 |
| ▸ | CCKBR | P32239 | 2/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2267540 | 0.88 | CCKBR (0.41) | CHRM1CCKBR | |
| SCHEMBL3234636 | 0.88 | CCKBR (0.41) | CHRM1CCKBR | |
| SCHEMBL607140 | 0.83 | CCKBR (0.56) | CHRM1CCKBR | |
| SCHEMBL2268176 | 0.78 | CHRM1 (0.40) | CHRM1CCKBRMAPTSMN1; SMN2 | |
| SCHEMBL2269267 | 0.78 | MEN1 (0.39) | CHRM1CCKBR | |
| SCHEMBL607671 | 0.74 | OPRK1 (0.47) | GAA | |
| SCHEMBL608046 | 0.73 | CCKBR (0.52) | CHRM1CCKBR | |
| SCHEMBL3226742 | 0.73 | CHRM1 (0.39) | CHRM1CCKBR | |
| SCHEMBL3233295 | 0.72 | CCKBR (0.43) | CHRM1CCKBR | |
| SCHEMBL2268380 | 0.71 | CCKBR (0.41) | CHRM1CCKBRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139331-A1 | COMPOSITIONS AND METHODS RELATING TO NOVEL COMPOUNDS AND TARGETS THEREOF | The Regents of the University of Michigan (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008112553-A1 | COMPOSITIONS AND METHODS RELATING TO NOVEL COMPOUNDS AND TARGETS THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2008-09-18 | — | — | WO | disclosed |