Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2264526 | 0.88 | CHRM1 (0.44) | CCKBRCHRM1MEN1LMNAALB | |
| SCHEMBL2268675 | 0.87 | MEN1 (0.43) | CCKBRCHRM1MEN1LMNAALB | |
| SCHEMBL2267642 | 0.87 | LMNA (0.44) | CCKBRCHRM1MEN1LMNAALB | |
| SCHEMBL2267540 | 0.83 | CCKBR (0.41) | CCKBRCHRM1MEN1LMNAALB | |
| SCHEMBL4101781 | 0.83 | CCKBR (0.61) | CCKBRCHRM1MEN1LMNAALB | |
| SCHEMBL11964628 | 0.83 | CCKBR (0.61) | CCKBRCHRM1MEN1LMNAALB | |
| SCHEMBL3225705 | 0.81 | OPRK1 (0.41) | CCKBRCHRM1LMNAALBLPAR1 | |
| SCHEMBL3231240 | 0.80 | CHRM1 (0.38) | CCKBRCHRM1MEN1LMNAALB | |
| SCHEMBL2268176 | 0.79 | CHRM1 (0.40) | CCKBRCHRM1MEN1LMNAALB | |
| SCHEMBL2269267 | 0.79 | MEN1 (0.39) | CCKBRCHRM1MEN1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217576-A2 | BENZODIAZEPINONE COMPOUNDS USEFUL IN THE TREATMENT OF SKIN CONDITIONS | The Regents of the University of Michigan (US) | 2010-08-18 | — | — | EP | claimed |
| WO-2009061916-A2 | BENZODIAZEPINONE COMPOUNDS USEFUL IN THE TREATMENT OF SKIN CONDITIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-05-14 | — | — | WO | claimed |