Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 5/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29812517 | 0.78 | GDA (0.41) | GDAALDH1A1PIM1PARP1SMN1; SMN2 | |
| SCHEMBL13219030 | 0.72 | — | — | |
| SCHEMBL20536023 | 0.72 | GDA (0.42) | GDAALDH1A1PIM1PARP1BCL2 | |
| SCHEMBL460243 | 0.72 | GDA (0.42) | GDAALDH1A1PIM1PARP1BCL2 | |
| SCHEMBL6765002 | 0.68 | — | — | |
| SCHEMBL10338263 | 0.68 | THRB (0.53) | POLBALDH1A1SMN1; SMN2LMNARAB9A | |
| SCHEMBL26672974 | 0.67 | GDA (0.41) | GDAALDH1A1PIM1PARP1BCL2 | |
| SCHEMBL24338103 | 0.66 | POLB (0.43) | GDAPOLBALDH1A1PIM1PARP1 | |
| SCHEMBL21393631 | 0.64 | GDA (0.43) | GDAALDH1A1PIM1PARP1BCL2 | |
| SCHEMBL14434857 | 0.64 | CYP1A2 (0.41) | POLBALDH1A1PARP1BCL2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476642-B | Compounds and their use for reducing uric acid levels | 阿奎斯特有限责任公司 | 2022-01-25 | — | — | CN | disclosed |
| CN-109476642-A | COMPOUNDS AND THEIR USE FOR REDUCING URIC ACID LEVELS | 阿奎斯特有限责任公司 | 2019-03-15 | — | — | CN | disclosed |