Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30172682 | 1.00 | KDM4E (0.46) | KDM4EMEN1MAPTKMT2ATAAR1 | |
| SCHEMBL20288135 | 0.80 | HPGD (0.48) | MEN1KMT2ACNR1ACHEHSD17B1 | |
| SCHEMBL883778 | 0.77 | ALDH1A1 (0.44) | KDM4EMEN1MAPTKMT2ACNR1 | |
| SCHEMBL30186296 | 0.77 | HSD17B1 (0.65) | ESR2CNR1HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL20557565 | 0.77 | RECQL (0.53) | KDM4EMEN1MAPTKMT2ACNR1 | |
| SCHEMBL30469298 | 0.77 | RECQL (0.53) | KDM4EMEN1MAPTKMT2ACNR1 | |
| SCHEMBL30963923 | 0.77 | HSD17B1 (0.65) | ESR2CNR1HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL198702 | 0.76 | TAAR1 (0.68) | KDM4EMEN1MAPTKMT2ATAAR1 | |
| SCHEMBL4244577 | 0.76 | DAO (0.44) | KDM4EKMT2ACNR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL12465771 | 0.76 | TAAR1 (0.53) | KDM4EMEN1MAPTKMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113614085-B | Inhibitors of influenza virus replication and uses thereof | 广东东阳光药业有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-113614085-A | Inhibitors of influenza virus replication and uses thereof | 广东东阳光药业有限公司 | 2021-11-05 | — | — | CN | disclosed |