Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14198883 | 0.84 | ALDH1A1 (0.41) | DAOGAAAPOBEC3GCNR1HPGD | |
| SCHEMBL883778 | 0.84 | ALDH1A1 (0.44) | DAOGAACNR1HPGDALDH1A1 | |
| SCHEMBL13802803 | 0.81 | ALAD (0.52) | CNR1ALDH1A1HTTKMT2ANPC1 | |
| SCHEMBL18869535 | 0.81 | ALAD (0.52) | CNR1HPGDALDH1A1ALOX12KDM4E | |
| SCHEMBL4244869 | 0.81 | CYP2A6 (0.48) | KDM4E | |
| SCHEMBL4478459 | 0.78 | KIF11 (0.50) | APOBEC3GHPGDALDH1A1HTTKDM4E | |
| SCHEMBL3711956 | 0.78 | HPGD (0.34) | DAOGAAAPOBEC3GCNR1HPGD | |
| SCHEMBL20288147 | 0.78 | DYRK1A (0.50) | CNR1 | |
| SCHEMBL20288145 | 0.76 | PIK3CD (0.44) | GAAHPGDALDH1A1ALOX12HTT | |
| SCHEMBL30963923 | 0.76 | HSD17B1 (0.65) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635781-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| US-7635781-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| EP-1926738-B1 | SYNTHESIS OF CYCLOPENTADIENEDITHIOPHENE DERIVATIVES | BASELL POLYOLEFINE GMBH (DE) | 2009-12-09 | — | — | EP | disclosed |
| EP-1926738-B1 | SYNTHESIS OF CYCLOPENTADIENEDITHIOPHENE DERIVATIVES | BASELL POLYOLEFINE GMBH (DE) | 2009-12-09 | — | — | EP | disclosed |
| US-20090118522-A1 | Synthesis of Cyclopentadienedithiophene Derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-05-07 | — | — | US | disclosed |
| US-20090118522-A1 | Synthesis of Cyclopentadienedithiophene Derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-05-07 | — | — | US | disclosed |
| US-20090118522-A1 | Synthesis of Cyclopentadienedithiophene Derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-05-07 | — | — | US | disclosed |
| US-20080287692-A1 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2008-11-20 | — | — | US | disclosed |
| US-20080287692-A1 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2008-11-20 | — | — | US | disclosed |
| EP-1387827-B1 | SYNTHESIS OF CYCLOPENTADIENE DERIVATIVES | BASELL POLYOLEFINE GMBH (DE) | 2008-09-24 | — | — | EP | disclosed |
| EP-1926738-A1 | SYNTHESIS OF CYCLOPENTADIENEDITHIOPHENE DERIVATIVES | Basell Polyolefine GmbH (DE) | 2008-06-04 | — | — | EP | disclosed |
| US-7253292-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2007-08-07 | — | — | US | disclosed |
| US-7253292-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2007-08-07 | — | — | US | disclosed |
| WO-2007033937-A1 | SYNTHESIS OF CYCLOPENTADIENEDITHIOPHENE DERIVATIVES | BASELL POLYOLEFINE GMBH (DE) | 2007-03-29 | — | — | WO | disclosed |
| WO-2007033937-A1 | SYNTHESIS OF CYCLOPENTADIENEDITHIOPHENE DERIVATIVES | BASELL POLYOLEFINE GMBH (DE) | 2007-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287692-A1 | Synthesis of cyclopentadiene derivatives | CYCS, CYC1, CBR1 | DAO 1360/4885GAA 4853/4885APOBEC3G 2194/4885 |
| US-20090118522-A1 | Synthesis of Cyclopentadienedithiophene Derivatives | CCNT1, CBR1, TST | DAO 921/4885GAA 4842/4885APOBEC3G 3302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.